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UnknownMechanisms Linking Physical Activity with Psychiatric Symptoms Across the Lifespan: A Systematic Review.
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S-EPMC10587276 | biostudies-literature
TranscriptomicsRNA-seq of intestinal crypts vs intestinal smooth muscle with a specific MMP17 deletion compared to wild-type
We wanted to assess the role of a specific smooth muscle protein (MMP17) in two different intestinal compartments, the epithelium (crypts) and the smooth muscle. To do that we isolate intestinal crypts from wild-type (WT) and knockout (KO, Mmp17-/-) mice, and obtained clean strips of smooth muscle. ...
ORGANISM(S): Mus musculus 
2021-09-27 | E-MTAB-9180 | biostudies-arrayexpress
TranscriptomicsHUMAN ENDOMETRIAL SIDE POPULATION CELLS EXHIBIT GENOTYPIC, PHENOTYPIC AND FUNCTIONAL FEATURES OF SOMATIC STEM CELLS
During reproductive life, the human endometrium undergoes around 480 cycles of growth, breakdown and regeneration should pregnancy not be achieved. This outstanding regenerative capacity is the basis for women’s cycling and its dysfunction may be involved in the etiology of pathological disorders. T...
ORGANISM(S): Homo sapiens 
2010-08-15 | E-GEOD-21633 | biostudies-arrayexpress
TranscriptomicsAnalysis of global gene expression profiles of A549 cells treated with SETX siRNA upon Influenza A/PR/8/34(ΔNS1) Infection
Untransfected (no siRNA), control siRNA or SETX siRNA treated A549 cells were infected with A/Puerto Rico/8/1934(ΔNS1) for 4 hours 3 Biological Replicates per condition
ORGANISM(S): Homo sapiens 
2015-03-30 | E-GEOD-52932 | biostudies-arrayexpress
TranscriptomicsAnalysis of global gene expression profiles of A549 cells treated with Xrn2 siRNA upon Influenza A/PR/8/34(ΔNS1) Infection
Untransfected (no siRNA), control siRNA or Xrn2 siRNA treated A549 cells were infected with A/Puerto Rico/8/1934(ΔNS1) for 4 hours 3 Biological Replicates per condition
ORGANISM(S): Homo sapiens 
2015-03-30 | E-GEOD-66661 | biostudies-arrayexpress
TranscriptomicsRNA-seq time-course of Calu-3 cells infected with SARS-CoV-2 early-lineage and Alpha variant viruses
Emergence of SARS-CoV-2 variants of concern (VOCs), including the globally successful Alpha (B.1.1.7) variant, suggests viral adaptation to enhance human-to-human transmission. Although much effort has focused on characterisation of spike changes, Alpha mutations outside spike likely contribute to a...
ORGANISM(S): Homo sapiens 
2021-12-31 | E-MTAB-11275 | biostudies-arrayexpress
TranscriptomicsSETX attenuates the antiviral innate immune response and controls viral biogenesis (GRO-Seq)
The innate immune response is the first line of defense against pathogens, and factors that control this cellular response represent targets for treating both infectious and inflammatory diseases. Here, we reveal a novel role for the human helicase SETX, also previously implicated in amyotrophic lat...
ORGANISM(S): Homo sapiens 
2015-03-30 | E-GEOD-52935 | biostudies-arrayexpress
TranscriptomicsAnalysis of global gene expression profiles of A549 cells treated with XRN2 siRNA under basal conditions
Untransfected (no siRNA), control siRNA or XRN2 siRNA treated A549 cells were analyzed for gene expression differences under basal conditions 3 Biological Replicates per condition
ORGANISM(S): Homo sapiens 
2015-03-30 | E-GEOD-66662 | biostudies-arrayexpress
TranscriptomicsAnalysis of global gene expression profiles of A549 cells treated with SETX siRNA under basal conditions
Untransfected (no siRNA), control siRNA or SETX siRNA treated A549 cells were analyzed for gene expression differences under basal conditions 3 Biological Replicates per condition
ORGANISM(S): Homo sapiens 
2015-03-30 | E-GEOD-52933 | biostudies-arrayexpress
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