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TranscriptomicsAnalysis of global gene expression profiles of hPAF1 deficient A549 cells during stimulation with PR8/∆NS1 influenza virus, IFNβ1 or Poly(I:C)
Viral infection is commonly associated with virus-driven hijacking of host proteins. We describe a novel mechanism by which influenza virus impacts host cells through the interaction of influenza NS1 protein with the infected cell epigenome. We show that the NS1 protein of influenza A H3N2 targets t...
ORGANISM(S): Homo sapiens 
2012-02-15 | E-GEOD-35267 | biostudies-arrayexpress
UnknownReply to S.A. Upadhyaya.
Not available
S-EPMC7526718 | biostudies-literature
TranscriptomicsSOX4 effect on LNCaP prostate cancer cells
This SuperSeries is composed of the following subset Series: GSE11874: Chromatin Immunoprecipitation microarray data from antiHA IP in stable LNCaP cells expressing either YFP or HA-SOX4/YFP GSE11913: Illumina expression data from LNCaP cells overexpressing either SOX4 or GFP GSE11914: Expression da...
ORGANISM(S): Homo sapiens 
2008-11-09 | E-GEOD-11915 | biostudies-arrayexpress
TranscriptomicsWhole-genome microarray analysis of human skin fibroblasts
Connective tissue growthfactor (CTGF/CCN2) is a matricellular protein induced by transforming growth factor-beta (TGF-beta) and intimately involved with tissue repair and overexpressed in various fibrotic conditions. We have previously shown that keratinocytes in vitro downregulate TGF-beta induced ...
ORGANISM(S): Homo sapiens 
2016-04-14 | E-GEOD-69447 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of gene expression changes in human A549 lung cancer cells upon siRNA knockdown of FAM60A and SDS3
The Sin3 histone deacetylase (HDAC) complex is a 1.2 MDa chromatin modifying complex that can repress transcription by binding to gene promoters and deacetylating histones. The Sin3/HDAC complex can affect cell cycle progression through multiple mechanisms and is among the targets of anticancer dru...
ORGANISM(S): Homo sapiens 
2012-09-15 | E-GEOD-39733 | biostudies-arrayexpress
TranscriptomicsAnalysis of global gene expression profiles of hPAF1 deficient A549 cells
This SuperSeries is composed of the following subset Series: GSE35265: Analysis of global gene expression profiles of hPAF1 deficiency on unstimulated A549 cells GSE35266: Analysis of global gene expression profiles of hPAF1 deficient A549 cells during infection with H1N1 influenza A virus or vesicu...
ORGANISM(S): Homo sapiens 
2012-02-15 | E-GEOD-35268 | biostudies-arrayexpress
TranscriptomicsChromatin Immunoprecipitation microarray data from antiHA IP in stable LNCaP cells expressing either YFP or HA-SOX4/YFP
SOX4 is a critical developmental transcription factor in vertebrates and is required for precise differentiation and proliferation in multiple tissues. In addition, SOX4 is overexpressed in many human malignancies, but the precise role of SOX4 in cancer progression is not well understood. He...
ORGANISM(S): Homo sapiens 
2008-11-09 | E-GEOD-11874 | biostudies-arrayexpress
UnknownA reference library for Canadian invertebrates with 1.5 million barcodes, voucher specimens, and DNA samples.
Not available
S-EPMC6897906 | biostudies-literature
TranscriptomicsOccupancy and transcriptional profile of Prdm12 in posteriorized neural tissue
V1 interneurons are a class of inhibitory neurons that play an essential role in vertebrate locomotion; however, the factors contributing to their specification are poorly understood. Morphological and molecular evidence suggest that the zinc finger transcription factor Prdm12 may play a role in pro...
ORGANISM(S): Xenopus laevis 
2015-11-04 | E-GEOD-64551 | biostudies-arrayexpress
TranscriptomicsAnalysis of global gene expression profiles of hPAF1 deficiency on unstimulated A549 cells
Viral infection is commonly associated with virus-driven hijacking of host proteins. We describe a novel mechanism by which influenza virus impacts host cells through the interaction of influenza NS1 protein with the infected cell epigenome. We show that the NS1 protein of influenza A H3N2 targets t...
ORGANISM(S): Homo sapiens 
2012-02-15 | E-GEOD-35265 | biostudies-arrayexpress
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