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TranscriptomicsTGF-b signaling and response
This work evaluates new and specific therapeutic targets and molecular diagnostic markers connected to the TGF-b response system in chronic fibrotic diseases.
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-579 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of mouse luminal uterine epithelium with knockout of ALK3
Bone morphogenetic proteins (BMPs) are transforming growth factor β (TGFβ) family members that regulate the post-implantation and mid-gestation stages of pregnancy. In this study we discovered that signaling via activin-like kinase 3 (ALK3/BMPR1A), a BMP type 1 receptor, is necessary for blastocys...
ORGANISM(S): Mus musculus 
2016-01-04 | E-GEOD-73717 | biostudies-arrayexpress
ProteomicsDynamics of single-cell protein covariation during epithelial-mesenchymal transition
Single cell proteomic dataset (~420 cells passing filter, 1827 proteins at 1% FDR and 4096 proteins post update via DART-ID) characterizing the Epithelial to Mesenchymal transition induced by TGF-B in MCF10A cells. Cells were sampled from day 0 (epithelial), day 3 (intermediate) and day 9 (sustaine...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000092872 | MassIVE
Transcriptomics18h before puparium formation vs. puparium formation tissue comparisons
Samples at 18h before puparium formation were compared to samples at puparium formation for each the following tissues: epidermis with attached muscle, salivary gland, wing disc, midgut, and central nervous system. Keywords = Drosophila, ecdysone, network, genomic, microarray, organogenesis, EcR, mi...
ORGANISM(S): Drosophila melanogaster 
2010-06-05 | E-GEOD-542 | biostudies-arrayexpress
TranscriptomicsEcR mutant midgut comparison
Comparisons between EcR mutant midgut and a reference control sample from mixed-stage normal midgut Keywords = Drosophila, ecdysone, network, genomic, microarray, organogenesis, EcR, midgut, central nervous system, salivary gland, epidermis, imaginal disc, development
ORGANISM(S): Drosophila melanogaster 
2010-06-05 | E-GEOD-540 | biostudies-arrayexpress
Transcriptomicssage gene RNAi experiment
Comparisons between the salivary glands upon the RNAi of sage gene vs. the control. Keywords = Drosophila, ecdysone, network, genomic, microarray, organogenesis, EcR, midgut, central nervous system, salivary gland, epidermis, imaginal disc, development
ORGANISM(S): Drosophila melanogaster 
2010-06-05 | E-GEOD-283 | biostudies-arrayexpress
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