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UnknownChemopreventive properties of 3,3'-diindolylmethane in breast cancer: evidence from experimental and human studies.
Not available
S-EPMC5059820 | biostudies-literature
TranscriptomicsGenome-wide transcriptome analysis of the dietary chemopreventive phytochemical sulforaphane on normal and prostate cancer cells.
Epidemiological studies provide strong evidence that consumption of cruciferous vegetables, such as broccoli, can significantly reduce the risk of developing cancers. Sulforaphane (SFN), a phytochemical derived from cruciferous vegetables, induces anti-proliferative and pro-apoptotic responses in pr...
ORGANISM(S): Homo sapiens 
2014-07-11 | E-GEOD-48812 | biostudies-arrayexpress
TranscriptomicsInvestigation of gene expression signature induced by Alk5TD (active type I TGF-beta receptor)
BT474 cells stably expressing Alk5TD or vector (BT474-Alk5TD and BT474-pBMN, respectively) were compared for gene expression. Genes that were differentially expressed between the two cell lines were collected as the signature induced by Alk5TD expression. Keywords: Comparison of two cell types (BT47...
ORGANISM(S): Homo sapiens 
2008-04-29 | E-GEOD-11293 | biostudies-arrayexpress
TranscriptomicsRNAi profiling of mouse loss of function mutant using in vivo screening identifies regulators of actin dynamics as key determinants of lymphoma progression
Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic experimentation. Here, we report the adaptation of loss of function screening to mouse models of cancer. U...
ORGANISM(S): Mus musculus 
2009-09-23 | E-GEOD-16090 | biostudies-arrayexpress
TranscriptomicsGenomeâ??wide transcriptional profiling with spatial resolution identifies Bone Morphogenetic Protein signaling as essential regulator of zebrafish cardiomyocyte regeneration.
In contrast to mammals, zebrafish regenerate heart injuries via proliferation of cardiomyocytes located at the wound border. Here, we show that tomo-seq can be used to identify whole-genome transcriptional profiles of the injury zone, the border zone and the healthy myocardium. Interestingly, the bo...
ORGANISM(S): Danio rerio 
2016-01-11 | E-GEOD-74652 | biostudies-arrayexpress
TranscriptomicsS mansoni infection B cell comparison
The helminth Schistosoma Mansoni is known to generate a regulatory B cell population that can suppress in multiple murine experimental models. Microarray comparison allows for a greater understanding as to how these cells are generated and their implications in immune regulation.
ORGANISM(S): Mus musculus 
2014-03-28 | E-MTAB-2100 | biostudies-arrayexpress
UnknownFertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome
Not available
S-SCDT-10_1038-S44321-024-00119-W | biostudies-other
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