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UnknownMutagenesis identifies the critical amino acid residues of human endonuclease G involved in catalysis, magnesium coordination, and substrate specificity.
Not available
S-EPMC2653514 | biostudies-literature
UnknownHedyotis diffusa Suppresses Colitis-Associated Colorectal Cancer via Inhibition of the IL-17A-IL-17RA Axis and NF-κB Signaling
Not available
S-EPMC12941307 | biostudies-literature
UnknownComprehensive assessment of host responses to ionizing radiation by nuclear factor-κB bioluminescence imaging-guided transcriptomic analysis.
Not available
S-EPMC3161058 | biostudies-literature
TranscriptomicsMicroarray analysis of aristolochic acid in normal human cells
Aim： Use microarray analysis to understand the molecular mechanism underlying the effect of aristolochic acid (AA), a major active component of plants from the Aristolochiaceae family, in normal human kidney (HK-2) cells. Methods： HK-2 cells were treated with AA for 24 hours and cell viability was ...
ORGANISM(S): Homo sapiens 
2010-09-24 | E-GEOD-18243 | biostudies-arrayexpress
TranscriptomicsAssessment of host responses to ionizing radiation
The aim of this study was to analyze the host responses to ionizing radiation by nuclear factor-κB (NF-κB) bioluminescence imaging-guided transcriptomic tool. Transgenic mice, carrying the NF-κB-driven luciferase gene, were exposed to a single dose of 8.5 Gy total-body irradiation. In vivo imaging s...
ORGANISM(S): Mus musculus 
2012-01-01 | E-GEOD-25208 | biostudies-arrayexpress
TranscriptomicsIdentification of a novel insulin receptor-binding protein from Momordica charantia by transcriptomic, proteomic, and docking analyses
Momordica charantia (MC) is a common vegetable in tropical areas and has been used for a long time as an alternative therapy for diabetes. Although several constituents of MC have displayed the hypoglycemic effects, the hypoglycemic targets of these constituents remain to be clarified. In this study...
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-39689 | biostudies-arrayexpress
TranscriptomicsExpression data from siRNA knockdown of Ehf in primary human corneal epithelial cells
Ehf is a transcriptional regulator that is highly expressed and enriched in corneal epithelium. To gain insights into the role of Ehf in the corneal epithelium, we performed siRNA knockdown of Ehf in primary human corneal epithelial cells. Primary human corneal epithelial cells were transfected with...
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-43157 | biostudies-arrayexpress
Unknown5-Fluorouracil induced intestinal mucositis via nuclear factor-κB activation by transcriptomic analysis and in vivo bioluminescence imaging.
Not available
S-EPMC3296709 | biostudies-literature
TranscriptomicsDNMT3L promotes quiescence in postnatal spermatogonial progenitor cells
We analyzed transcriptome profiles of postnatal germ cells and demonstrated that DNMT3L is important for spermatogonial stem/progenitor cell development Examination of wild-type and Dnmt3l knockout smaples in postnatal male germ cells
ORGANISM(S): Mus musculus 
2014-07-03 | E-GEOD-54411 | biostudies-arrayexpress
UnknownStearoyl-CoA desaturase inhibition normalizes brain lipid saturation, α-synuclein homeostasis, and motor function in mutant Gba1-Parkinson mice.
Not available
S-EPMC12288896 | biostudies-literature
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