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MetabolomicsAbsorption efficiency of RESV through mouse skin using 3 bases in different tissues
Resveratrol (RESV) is a plant polyphenol, which is thought to have beneficial metabolic effects in laboratory animals as well as in humans. Following oral administration, RESV is immediately catabolized, resulting in low bioavailability. This study compared RESV metabolites and their tissue distribu...
2014-12-15 | MTBLS126 | MetaboLights
TranscriptomicsA Xenopus DNA microarray approach to identify novel direct BMP target genes involved in early embryonic development
Bone Morphogenetic Proteins (BMPs), a subgroup of the TGF- superfamily, were originally isolated from bone on the basis of their ability to induce ectopic bone development. While BMPs are involved in a wide range of developmental and physiological functions, very few vertebrate target genes in t...
ORGANISM(S): Xenopus laevis 
2010-06-10 | E-GEOD-2274 | biostudies-arrayexpress
ProteomicsIn vitro reconstitution of epigenetic reprogramming in the human germ line
M1-BTAG iPSCs or TET1-KO iPSCs were analyzed by 8% SDS-PAGE, followed by trypsin digestion and LC/MS/MS with an Orbitrap Fusion Lumos linked with an Ultimate 3000 pump and HTC-PAL autosampler. Acquired data files were processed using FragPipe v20.0 (MSFragger v3.8, Philosopher v5.0.0, IonQuant v1.9....
ORGANISM(S): Homo Sapiens (human) 
2024-04-25 | PXD048118 | JPOST Repository
UnknownUltrasound-guided glenohumeral joint injections for shoulder pain in ALS: A case series.
Not available
S-EPMC9940635 | biostudies-literature
UnknownA Randomized Phase 2 Study of 5-Aminolevulinic Acid Hydrochloride and Sodium Ferrous Citrate for the Prevention of Nephrotoxicity Induced by Cisplatin-Based Chemotherapy of Lung Cancer.
Not available
S-EPMC9808709 | biostudies-literature
UnknownThe frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities.
Not available
S-EPMC10876563 | biostudies-literature
UnknownIdentifying long-term stable refugia for relict plant species in East Asia.
Not available
S-EPMC6203703 | biostudies-literature
TranscriptomicsA DNA Hypomethylation Signature Predicts Novel Anti-Tumor Activity of LSD1 Inhibitors in SCLC (BeadChip)
Epigenetic dysregulation has emerged as an important mechanism in cancer. Alterations in epigenetic machinery have become a major focus for new targeted therapies. The current report describes the discovery and biological activity of a cyclopropylamine containing inhibitor of Lysine Demethylase 1 ...
ORGANISM(S): Homo sapiens 
2015-07-14 | E-GEOD-66295 | biostudies-arrayexpress
TranscriptomicsA DNA Hypomethylation Signature Predicts Novel Anti-Tumor Activity of LSD1 Inhibitors in SCLC (microarray)
Epigenetic dysregulation has emerged as an important mechanism in cancer. Alterations in epigenetic machinery have become a major focus for new targeted therapies. The current report describes the discovery and biological activity of a cyclopropylamine containing inhibitor of Lysine Demethylase 1 ...
ORGANISM(S): Homo sapiens 
2015-07-14 | E-GEOD-66294 | biostudies-arrayexpress
GenomicsA DNA Hypomethylation Signature Predicts Novel Anti-Tumor Activity of LSD1 Inhibitors in SCLC (ChIP-Seq)
Epigenetic dysregulation has emerged as an important mechanism in cancer. Alterations in epigenetic machinery have become a major focus for new targeted therapies. The current report describes the discovery and biological activity of a cyclopropylamine containing inhibitor of Lysine Demethylase 1 ...
ORGANISM(S): Homo sapiens 
2015-07-14 | E-GEOD-66297 | biostudies-arrayexpress
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