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TranscriptomicsTranscription profiling of mouse wild type and Lim1-null renal vesicles microdissected from embryonic day 12.5 kidneys
The Lim1 gene has essential functions during several stages of kidney development. In particular, a tissue specific knockout in the early metanephric mesenchyme results in the formation of the earliest nephron precursor, the renal vesicle, but failure of this structure to progress to the next stage,...
ORGANISM(S): Mus musculus 
2007-12-12 | E-GEOD-7257 | biostudies-arrayexpress
UnknownVascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy.
Not available
S-EPMC3178293 | biostudies-literature
TranscriptomicsRNA-Seq of transgenic rice (Oryza sativa spp. japonica cultivar Kitaake) plants containing a single construct that over-expresses C4 metabolic pathway components CA, PEPC, MDH, ME and PPDK
Transcriptome sequencing of transgenic and wild type plants to assess the patterns of altered gene expression associated with over expression of the 5 core C4 cycle metabolic pathway components – CA, PEPC, MDH, ME and PPDK.
ORGANISM(S): Oryza sativa Japonica Group 
2022-05-28 | E-MTAB-9129 | biostudies-arrayexpress
UnknownComparison of psychedelic and near-death or other non-ordinary experiences in changing attitudes about death and dying.
Not available
S-EPMC9401141 | biostudies-literature
TranscriptomicsRNAseq of Human Umbilical Vein Endothelial Cells treated with Insulin in the presence or absence of TGF-beta kinase inhibitor SB431542 for 90 minute.
Endothelial cells play many important role during development and development of diseases. Endothelial dysfunction which is commonly seen in diabetes patients is thought to be one of the first step that leads to adverse events such as retinopathy, nephropathy, and atherosclerosis. To examine to whic...
ORGANISM(S): Homo sapiens 
2019-01-15 | E-MTAB-6841 | biostudies-arrayexpress
UnknownPentaerythritol Tetranitrate In Vivo Treatment Improves Oxidative Stress and Vascular Dysfunction by Suppression of Endothelin-1 Signaling in Monocrotaline-Induced Pulmonary Hypertension.
Not available
S-EPMC5350298 | biostudies-literature
TranscriptomicsArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
RELEVANCE: Smith-Lemli-Opitz syndrome (SLOS) is a human disease caused by mutations in the gene coding for the enzyme DHCR7 (7-dehydrocholesterol (7DHC) reductase), which catalyzes the final step of cholesterol biosynthesis. Accumulated 7DHC in tissues and body fluids of SLOS patients gives rise t...
ORGANISM(S): Mus musculus 
2021-03-20 | E-MTAB-10055 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of MCF-7 cells treated with Si-Wu-Tang, estradiol and ferulic acid
Traditional Chinese medicines (TCM), usually composed of a mixture of components, may simultaneously target multiple genes/pathways and thus achieve superior efficacy for complex diseases such as cancer. To identify novel mechanisms of action and potential health benefits for a TCM formula Si-Wu-Tan...
ORGANISM(S): Homo sapiens 
2011-05-18 | E-GEOD-23610 | biostudies-arrayexpress
UnknownMolecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma.
Not available
S-EPMC6369924 | biostudies-literature
TranscriptomicsmicroRNA and mRNA expression profiles of human embryonic stem cells treated with activin A
Human embryonic stem (hES) cells have the capacities to propagate for extended periods and to differentiate into cell types from all three germ layers both in vitro and in vivo. These characteristics of self-renewal and pluripotency enable hES cells having the potential to provide an unlimited suppl...
ORGANISM(S): Homo sapiens 
2010-09-10 | E-GEOD-16910 | biostudies-arrayexpress
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