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TranscriptomicsChitosan-affected gene expression profiles in brain and stomach
Chitosan has been widely used in food industry as a weight-loss aid and a cholesterol-lowering agent. Previous studies have shown that chitosan affects metabolic responses and contributes to anti-diabetic, hypocholestermic, and blood glucose-lowering effects; however, the in vivo targeting sites and...
ORGANISM(S): Mus musculus 
2014-10-29 | E-GEOD-33565 | biostudies-arrayexpress
TranscriptomicsA novel insulin receptor-binding protein enhances glucose uptake and glucose clearance in vitro and in vivo through triggering insulin receptor signaling pathway
In this study, a novel IR-binding protein (IRBP) from Momordica charantia, named as mcIRBP, was identified by analyzing the physical and functional interactions between mcIRBP and IR. The hypoglycemic effect and mechanism of mcIRBP were further evaluated in normal and streptozotocin-induced diabetic...
ORGANISM(S): Mus musculus 
2016-06-25 | E-GEOD-48274 | biostudies-arrayexpress
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