Sort   by:  
 Page size 
Genomicsena-DATASET-MUG-26-02-2014-10:25:52:632-26 - samples
In this study we performed whole genome sequencing of plasma DNA (plasma-Seq) of 19 plasma-DNA samples from a total of 10 patients treated with anti-EGFR therapy. We demonstrated that development of resistance to anti-EGFR therapies is frequently associated with focal amplifications of KRAS, MET, an...
EGAD00001000748 | EGA
Genomicsena-DATASET-MUG-29-10-2013-10:52:10:827-14 - samples
In this study we performed ultra deep sequencing of genes associated with anti-EGFR resistance, such as KRAS, BRAF, PIK3CA, and EGFR in 17 plasma-DNA samples from a total of 10 patients treated with anti-EGFR therapy.
EGAD00001000688 | EGA
Genomicsena-DATASET-MUG-17-05-2013-08:29:19:239-74 - samples
We performed serial plasma-Seq analyses on a male who progressed from castration-sensitive to castration-resistant prostate cancer within 10 months following treatment with androgen-deprivation therapy.
EGAD00001000396 | EGA
Genomicsena-DATASET-MUG-19-03-2013-14:10:31:964-87 - samples
We performed low coverage whole genome sequencing of plasma DNA from prostate cancer patients to establish copy number profiles on both a genome-wide and a gene-specific level. The data include plasma samples from prostate cacner patients (n=13), non-malignant controls (males, n=10 and females, n=9)...
EGAD00001000364 | EGA
Genomicsena-DATASET-MUG-19-03-2013-14:14:47:994-92 - samples
In this study we analysed patients with metastatic prostate cancer to scan their tumor genomes noninvasively in plasma DNA. We enriched 1.3 Mbp of seven plasma DNAs (4 CRPC cases: CRPC1-3 and CRPC5; 3 CSPC cases: CSPC1-2 and CSPC4) including exonic sequences of 55 cancer genes and 38 introns of 18 g...
EGAD00001000365 | EGA
Genomicsena-DATASET-MUG-11-09-2014-07:42:30:338-15 - samples
Exome sequencing of peripheral blood from 4 individuals of a family with familial colorectal cancer type X
EGAD00001001009 | EGA
Genomicsena-DATASET-MUG-11-09-2014-07:45:47:901-16 - samples
Sequencing of colorectal tumors and normal tissue using Ion AmpliSeq Cancer Hotspot Panel V2
EGAD00001001010 | EGA
GenomicsResistance to anti-EGFR therapy in colorectal cancer
Monoclonal antibodies targeting the Epidermal Growth Factor Receptor (EGFR), such as cetuximab and panitumumab, have evolved to important therapeutic options in metastatic colorectal cancer (CRC). However, almost all patients with clinical response to anti-EGFR therapies show disease progression wit...
EGAS00001000582 | EGA
GenomicsPlasma-Seq of patients with metastatic prostate cancer
Study 1 In this study we analysed patients with metastatic prostate cancer to scan their tumor genomes noninvasively in plasma DNA. We wanted to make whole-genome analysis from plasma DNA amenable to clinical routine applications and developed an approach based on a benchtop high-throughput platform...
EGAS00001000451 | EGA
GenomicsIdentification of mutations and structural rearrangements in plasma DNA form metastatic prostate cancer patients
In this study we analysed patients with metastatic prostate cancer to scan their tumor genomes noninvasively in plasma DNA. We enriched 1.3 Mbp of seven plasma DNAs (4 CRPC cases: CRPC1-3 and CRPC5; 3 CSPC cases: CSPC1-2 and CSPC4) including exonic sequences of 55 cancer genes and 38 introns of 18 g...
EGAS00001000453 | EGA
Sort   by:  
 Page size