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UnknownEvaluation of smartphone-based testing to generate exploratory outcome measures in a phase 1 Parkinson's disease clinical trial.
Not available
S-EPMC6175318 | biostudies-literature
UnknownInfluence of Solid Oral Dosage Form Characteristics on Swallowability, Visual Perception, and Handling in Older Adults.
Not available
S-EPMC10142368 | biostudies-literature
UnknownCost-effectiveness Analysis of Ocrelizumab for the Treatment of Relapsing and Primary Progressive Multiple Sclerosis in Portugal.
Not available
S-EPMC10043078 | biostudies-literature
UnknownImpact of Tablet Size and Shape on the Swallowability in Older Adults.
Not available
S-EPMC10145850 | biostudies-literature
ProteomicsThe Legionella-driven PtdIns(4)P gradient at LCV-ER membrane contact sites promotes Vap-, OSBP and Sac1-dependent pathogen vacuole remodeling
The causative agent of Legionnaires’ disease, Legionella pneumophila, governs interactions with host cells by secreting ca. 330 different “effector” proteins. The facultative intracellular bacteria replicate in macrophages and amoeba within a unique compartment, the Legionella-containing vacuole (LC...
ORGANISM(S): Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Dictyostelium discoideum 
2023-02-21 | PXD034490 | Pride
Large fusion gtpase Oxysterol binding protein Legionella pneumophila Atlastin Legionnaires’ disease Host-pathogen interaction Pathogen vacuole Amoeba Dictyostelium discoideum 
UnknownPatient-reported outcome results from the open-label phase III AURELIA trial evaluating bevacizumab-containing therapy for platinum-resistant ovarian cancer.
Not available
S-EPMC4876313 | biostudies-literature
ProteomicsProteomic characterization of cerebrospinal fluid in patients with brain malignancies
Recent technological advances in molecular diagnostics through liquid biopsies hold the promise to monitor tumor evolution and treatment response of brain malignancies without the need of invasive surgical tissue accrual. Here, we implemented a new mass spectrometry-based protein analysis pipeline a...
ORGANISM(S): Homo sapiens (Human) 
2021-03-25 | PXD021984 | Pride
Brain tumor Glioblastoma Proteome Biomarker 
TranscriptomicsNon-circadian expression masking clock-driven weak transcription rhythms in U2OS cells
U2OS cells harbor a circadian clock but express only a few rhythmic genes in constant conditions. We identified 3040 binding sites of the circadian regulators BMAL1, CLOCK and CRY1 in the U2OS genome. Most binding sites even in promoters do not correlate with detectable rhythmic transcript levels. L...
ORGANISM(S): Homo sapiens 
2014-05-23 | E-GEOD-57891 | biostudies-arrayexpress
TranscriptomicsIntratumor heterogeneity of gene expression profiles in early stage non-small cell lung cancer (NSCLC)
Gene expression profiling of NSCLC tissues let to the establishment of several prognostic, predictive gene signatures with little overlap. To study factors introducing variability into gene expression microarray studies we compared interpatient (patient-to-patient) and intrapatient (tumor sub-sample...
ORGANISM(S): Homo sapiens 
2014-09-23 | E-GEOD-33532 | biostudies-arrayexpress
UnknownSHIP-MR and Radiology: 12 Years of Whole-Body Magnetic Resonance Imaging in a Single Center.
Not available
S-EPMC8775435 | biostudies-literature
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