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TranscriptomicsExpression Data from BALB/c and Stat6-deficient bone marrow derived macrophages (BMDM)
We used microarrays to find Stat6 dependent genes in control and IL-4 exposed bone marrow derived macrophages. Alternatively activated macrophages (AAM) accumulate in tissues during Th2-associated immune responses like helminth infections and allergic disorders. These cells possess potent inhibitor...
ORGANISM(S): Mus musculus 
2010-07-19 | E-GEOD-20030 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression profiles between human and mouse monocyte subsets [mouse data]
Human and mouse blood each contain two monocyte subsets. Here, we investigated the extent of their similarity using a microarray approach. Approximately 300 genes in human and 550 genes in mouse were differentially expressed between subsets. More than 130 of these gene expression differences were co...
ORGANISM(S): Mus musculus 
2009-12-03 | E-GEOD-17256 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae temperature sensitive eIF5A mutant shows accumulation of transcripts targeted to the Nonsense Mediated Decay pathway
The highly conserved protein eIF5A found in archaea and all eucaryotes uniquely contains the posttranslationally formed amino acid hypusine. Despite being essential the functions of this protein and its modification remain unclear. To gain more insight into these functions temperature sensitive muta...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-13 | E-GEOD-5290 | biostudies-arrayexpress
UnknownGender- and sex-sensitive psychopharmacotherapy of alcohol use disorder: a systematic review and meta-analysis protocol.
Not available
S-EPMC12682176 | biostudies-literature
TranscriptomicsIdentification of KSHV, EBV and cellular miRNA targets in human B-cells using RIP-Chip
RIP-Chip was performed on DG75-eGFP, DG75-10/12, BCBL-1, BL41, BL41 B95.8 and Jijoye using anti-human Ago2 (11A9) antibodies. Anti-BrdU antibodies were used as controls for DG75-eGFP, DG75-10/12 and BCBL-1. Total RNA was used as control for BL41, BL41 B95.8 and Jijoye. Samples were analyzed on Affym...
ORGANISM(S): Homo sapiens 
2011-02-04 | E-GEOD-17180 | biostudies-arrayexpress
GenomicsAntigen-specific T helper cells predict intensity and longevity of immune responses to SARS-CoV-2 booster vaccination
Antigen-specific T helper cells predict intensity and longevity of immune responses to SARS-CoV-2 booster vaccination
PRJNA1144424 | ENA
TranscriptomicsGene expression profiling on bronchoalveolar lavage (BAL) cells treated with all-trans-retinoic acid (ATRA)
All-trans retinoic acid (ATRA) is a potent retinoid, which has been used successfully in different clinical settings as a potential drug to treat COPD and emphysema. In alveolar macrophages, ATRA selectively down-regulates MMP-9 and up-regulates TIMP-1 expression. In the present study, we analyzed a...
ORGANISM(S): Homo sapiens 
2010-09-04 | E-GEOD-23704 | biostudies-arrayexpress
UnknownDihydrotestosterone and Finasteride Effects on Alcohol Cue-Elicited Brain Activity in Males With Heavy Episodic Drinking.
Not available
S-EPMC12848907 | biostudies-literature
UnknownA viral glycoprotein targets IgG<sup>+</sup> memory B cells to mediate humoral immune evasion.
Not available
S-EPMC12905349 | biostudies-literature
GenomicsDissection of the molecular complexity of colorectal cancer in pre-clinical models identifies predictive signatures of sensitivity to EGFR inhibitors
Colorectal carcinoma (CRC) is a heterogeneous tumour entity, with only a fraction of the tumours responding to currently available therapies. A detailed understanding of the biology and genetics of CRC is a prerequisite for precision medicine. To address this challenge in clinical oncology, the Onco...
EGAS00001001752 | EGA
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