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Proteomicsthermal proteome profiling study on Haemonchus contortus
Parasitic diseases of humans and other animals represent a major socioeconomic burden worldwide. In humans, parasitic worms (helminths) that cause neglected tropical diseases (NTDs) affect ~ billion people, equating to a burden of >12 million disability-adjusted life years (DALYs) (Hotez et al., 201...
ORGANISM(S): Caenorhabditis elegans 
2022-09-25 | PXD034868 | Pride
Haemonchus contortus  tpp  lc-ms/ms 
ProteomicsABX464 – structure-activity relationship in a model parasitic nematode and target deconvolution
Within the context of our anthelmintic discovery program, we recently identified and evaluated a quinoline derivative, called ABX464 or obefazimod, as a nematocidal candidate; synthesised a series of analogues which were assessed for activity against the free-living model nematode Caenorhabditis ele...
ORGANISM(S): Haemonchus contortus (Barber pole worm) 
2024-02-07 | PXD046553 | Pride
Nematode Lc-ms/ms 
TranscriptomicsAn atlas of active enhancers across human cell types and tissues
Sequencing of 5' ends of RNA molecules from control and exosome-depleted HeLa-S3 cells. CAGE library construction from RNA extracted from control and exosome-depleted cells.
ORGANISM(S): Homo sapiens 
2014-03-26 | E-GEOD-49834 | biostudies-arrayexpress
UnknownSafety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial.
Not available
S-EPMC11838922 | biostudies-literature
UnknownPEEP-AKI-COVID ICU: Effect of positive end-expiratory pressure on acute kidney injury development in patients with COVID-19-associated acute respiratory distress syndrome: an ancillary analysis of the COVID-ICU study.
Not available
S-EPMC12574259 | biostudies-literature
UnknownEPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI): study protocol for a multicentre, observational trial.
Not available
S-EPMC8718477 | biostudies-literature
UnknownGlobal anaesthesia practice using inguinal hernia surgery as a tracer condition: a secondary analysis of an international prospective cohort study.
Not available
S-EPMC12519944 | biostudies-literature
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