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TranscriptomicsERG induced mesenchymal like gene signature
ERG overexpression was conducted in stably transfected K562 cell line with a tet-on inducible plasmid habouring ERG3. Prolonged induction of ERG (8 days) produced spindle cell shape changes whereas non-induced cells retained the round morphology. In oder to determine the genes responsible for induci...
ORGANISM(S): Homo sapiens 
2013-10-19 | E-GEOD-51258 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for myelodysplastic syndromes (MDS) and related neoplasms
In this study, to obtain a complete registry of genetic lesions in MDS and to identify novel therapeutic targets, we performed SNP array analysis and whole exome analysis for novel mutations using high-throughput sequencing technologies. In whole exome analysis, paired CD3-positive T cells were used...
ORGANISM(S): Homo sapiens 
2011-09-11 | E-GEOD-31174 | biostudies-arrayexpress
UnknownClonal Evolution and Blast Crisis Correlate with Enhanced Proteolytic Activity of Separase in BCR-ABL b3a2 Fusion Type CML under Imatinib Therapy.
Not available
S-EPMC4472749 | biostudies-literature
UnknownOlder patients with chronic myeloid leukemia (≥65 years) profit more from higher imatinib doses than younger patients: a subanalysis of the randomized CML-Study IV.
Not available
S-EPMC4050299 | biostudies-literature
UnknownStatistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients.
Not available
S-EPMC9769467 | biostudies-literature
UnknownMeta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
Not available
S-EPMC4125087 | biostudies-literature
UnknownPlasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer: the STAMPEDE Phase 3 Randomized Clinical Trial.
Not available
S-EPMC11869088 | biostudies-literature
UnknownMetformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol.
Not available
S-EPMC12303861 | biostudies-literature
UnknownRetrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Not available
S-EPMC7505971 | biostudies-literature
UnknownThe landscape of viral associations in human cancers.
Not available
S-EPMC8076016 | biostudies-literature
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