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GenomicsSelective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers [Affymetrix]
Chromatin regulators have become highly attractive targets for cancer therapy, yet many of these regulators are expressed in a broad range of healthy cells and contribute generally to gene expression. An important conundrum has thus emerged: how can inhibition of a general regulator of gene express...
ORGANISM(S): Homo sapiens 
2013-03-07 | E-GEOD-44929 | biostudies-arrayexpress
TranscriptomicsTranscriptional super-enhancers connected to cell identity and disease
Super-enhancers are large clusters of transcriptional enhancers that drive expression of genes that control and define cell identity. Improved understanding of the roles super-enhancers play in biology would be afforded by knowing the constellation of factors that constitute these domains and by ide...
ORGANISM(S): Homo sapiens 
2013-10-23 | E-GEOD-51522 | biostudies-arrayexpress
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