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TranscriptomicsEffects of Lipocalin 2 (Lcn2), iron, and the bacterial siderophore Enterobactin on A549 respiratory cell gene expression
Iron is essential for many cellular processes and is required by bacteria for replication. To acquire iron from the host, pathogenic Gram-negative bacteria secrete siderophores, including Enterobactin (Ent). However, Ent is bound by the host protein Lipocalin 2 (Lcn2), preventing bacterial reuptake ...
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-54962 | biostudies-arrayexpress
UnknownEffect of patient navigation on satisfaction with cancer-related care.
Not available
S-EPMC4767607 | biostudies-literature
TranscriptomicsCD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
Systemic inflammation like in sepsis is still lacking specific diagnostic markers and effective therapeutics. The first line of defense against intruding pathogens and endogenous damage signals is pattern recognition by e.g., complement and Toll-like receptors (TLR). Combined inhibition of a key com...
ORGANISM(S): Homo sapiens 
2015-01-08 | E-GEOD-55537 | biostudies-arrayexpress
TranscriptomicsMembranous Expression of Ectodomain Isoforms of the Epidermal Growth Factor Receptor (EGFR) Predicts Outcome after Chemoradiotherapy of Lymph Node Negative Cervical Cancer
We compared the prognostic significance of ectodomain isoforms of the epidermal growth factor receptor (EGFR), which lack the tyrosine kinase (TK) domain, with that of the full length receptor and its autophosphorylation status in cervical cancers treated with conventional chemoradiotherapy. We furt...
ORGANISM(S): Homo sapiens 
2011-07-18 | E-GEOD-29817 | biostudies-arrayexpress
TranscriptomicsGenomic Loss of Penicillin-Binding Protein 3 in Burkholderia pseudomallei Confers Clinical Resistance to Ceftazidime
Array-CGH analysis and Burkholderia pseudomallei isolates pre and post ceftazidime relapse. Genomic DNA from both the parental strains and variant strains were labeled with Cy3 or Cy5 fluorescent dyes and hybridized onto a customized microarray with probes designed from the reference Bp K96243 genom...
ORGANISM(S): Burkholderia pseudomallei 
2011-10-06 | E-GEOD-25832 | biostudies-arrayexpress
TranscriptomicsIdentification of eight candidate target genes of the prognsotic 3p loss in cervical cancer by integrative genomic profiling
We performed integrative gene dosage and expression profiling to identify candidate target genes of the prognostic 3p loss in cervical cancer. Candidate target genes were proposed from the correlation between gene dosage and gene expression. Combined network, gene set, and gene ontology analysis of ...
ORGANISM(S): Homo sapiens 
2013-02-28 | E-GEOD-38964 | biostudies-arrayexpress
TranscriptomicsHypoxia-induced gene expression in chemoradioresistant cervical cancer revealed by dynamic contrast enhanced MRI
We explored the prognostic impact of the dynamic contrast enhanced MR imaging (DCE-MRI) parameter ABrix in cervical cancer combined with global gene expression data to reveal the underlying molecular phenotype of the parameter and construct a gene signature that reflected ABrix. Based on 78 cervical...
ORGANISM(S): Homo sapiens 
2012-08-16 | E-GEOD-36562 | biostudies-arrayexpress
TranscriptomicsGene expression profile of PBMCs after intake of fish oil for seven weeks compared to high oleic sunflower oil
Fish oil supplementation has been shown to alter gene expression of mononuclear cells both in vitro and in vivo. However, little is known about the total transcriptomic profile in healthy subjects after intake of fish oil compared to a control group. The objective was to examine the gene expression ...
ORGANISM(S): Homo sapiens 
2014-05-01 | E-GEOD-48368 | biostudies-arrayexpress
TranscriptomicsEffects of TiO2 and Ag nanoparticles on polyhydroxybutyrate biosynthesis by activated sludge bacteria
Manufactured nanomaterials (MNMs) are increasingly incorporated into consumer products that are disposed into sewage. In wastewater treatment, MNMs adsorb to activated sludge biomass where they may impact biological wastewater treatment performance, including nutrient removal. Here, we studied MNM e...
ORGANISM(S): mixed sample 
2014-12-03 | E-GEOD-63781 | biostudies-arrayexpress
UnknownRapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis.
Not available
S-EPMC2705793 | biostudies-literature
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