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GenomicsCo-transcriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate
Various histone modifications decorate nucleosomes within transcribed genes. Among these, monoubiquitylation of histone H2B (H2Bub1) and methylation of histone H3 on lysines 36 (H3K36me2/3) and 79 (H3K79me2/3) correlate positively with gene expression. By measuring the progression of the transcripti...
ORGANISM(S): Homo sapiens 
2014-07-15 | E-GEOD-56279 | biostudies-arrayexpress
TranscriptomicsPosition-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB (HJAY)
To gain global insights into the role of the well-known repressive splicing regulator PTB we analyzed the consequences of PTB knockdown in HeLa cells using high-density oliogonucleotide splice-sensitive microarrays. The major class of identified PTB-regulated splicing event was PTB-repressed cassett...
ORGANISM(S): Homo sapiens 
2010-09-01 | E-GEOD-23513 | biostudies-arrayexpress
TranscriptomicsPosition-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB (Exon array)
To gain global insights into the role of the well-known repressive splicing regulator PTB we analyzed the consequences of PTB knockdown in HeLa cells using high-density oliogonucleotide splice-sensitive microarrays. The major class of identified PTB-regulated splicing event was PTB-repressed cassett...
ORGANISM(S): Homo sapiens 
2010-09-01 | E-GEOD-23514 | biostudies-arrayexpress
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