Sort   by:  
 Page size 
TranscriptomicsGlobal expression profiling of CD4 T-cell responses to house dust mite allergens in human atopics and nonatopics.
The aim of this study was to employ a systems-level analysis to elucidate gene expression networks operating in the CD4 T-cell responses which underpin human atopic disease. Keywords: Disease state analysis; T-cell response The study design consisted of 45 subjects, including 30 HDM-sensitized atop...
ORGANISM(S): Homo sapiens 
2009-05-05 | E-GEOD-14908 | biostudies-arrayexpress
TranscriptomicsImmune response eQTL study in human neonatal myeloid cells and T cells
Gene expression microarray data in resting myeloid cells and CD4+ T cells, as well as in response to lipopolysaccharide (LPS) or phytohemagglutinin (PHA) stimulation for 24 hours, respectively. Myeloid cells and CD4+ T cells were purified from resting and stimulated peripheral blood mononuclear cell...
ORGANISM(S): Homo sapiens 
2020-04-20 | E-MTAB-8977 | biostudies-arrayexpress
TranscriptomicsPneumococcal conjugate vaccination at birth induces robust recall responses at 9 months of age.
The objective of this study was to compare recall responses to vaccine antigens at 3 months and 9 months of age in infants who were vaccinated at birth or at 1 month. PBMC were obtained at 9 months of age from infants who were vaccinated at birth (n=25) or 1 month (n=25). The PBMC were cultured in t...
ORGANISM(S): Homo sapiens 
2011-06-27 | E-GEOD-25263 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of CD4 T cells and CD45+ HLA-DR+ cells during experimental allergic rhinitis in humans.
Six patients with seasonal allergic rhinitis were challenged daily for 8 days with birch pollen extract. A mucosal biopsy was obtained from one nostril at basline (day 0) and from the other nostril after allergen challenge (day 9). The mucosal biopsies were digested into single cells, and then sorte...
ORGANISM(S): Homo sapiens 
2015-09-01 | E-GEOD-49782 | biostudies-arrayexpress
TranscriptomicsOncogenic Activation Of FOXR1 by 11q23 Intrachromosomal Deletion-Fusions In Neuroblastoma
Neuroblastoma tumors frequently show loss of heterozygosity of chromosome 11q with a shortest region of overlap in the 11q23 region. These deletions are thought to cause inactivation of tumor suppressor genes leading to haploinsufficiency. Alternatively, micro-deletions could lead to gene fusion p...
ORGANISM(S): Homo sapiens 
2012-05-31 | E-GEOD-29634 | biostudies-arrayexpress
TranscriptomicsDevelopment and Independent Validation of a Prognostic Assay for Stage II Colon Cancer using Formalin Fixed Paraffin Embedded Tissue_Validation Set
Current prognostic factors are poor at identifying patients at risk of disease recurrence following surgery for stage II colon cancer. Here we describe a DNA microarray based prognostic assay using clinically relevant formalin fixed paraffin embedded (FFPE) samples.
ORGANISM(S): Homo sapiens 
2011-11-22 | E-MTAB-864 | biostudies-arrayexpress
TranscriptomicsDevelopment and Independent Validation of a Prognostic Assay for Stage II Colon Cancer using Formalin Fixed Paraffin Embedded Tissue_Training Set
Current prognostic factors are poor at identifying patients at risk of disease recurrence following surgery for stage II colon cancer. Here we describe a DNA microarray based prognostic assay using clinically relevant formalin fixed paraffin embedded (FFPE) samples.
ORGANISM(S): Homo sapiens 
2011-11-22 | E-MTAB-863 | biostudies-arrayexpress
UnknownRNA-Seq Analysis of Gene Expression, Viral Pathogen, and B-Cell/T-Cell Receptor Signatures in Complex Chronic Disease.
Not available
S-EPMC5850034 | biostudies-literature
UnknownAssociation of the IL-10 gene family locus on chromosome 1 with juvenile idiopathic arthritis (JIA).
Not available
S-EPMC3475696 | biostudies-literature
UnknownGenome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
Not available
S-EPMC4091986 | biostudies-literature
Sort   by:  
 Page size