Homeodomain - OmicsDI

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Lab affiliation

1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. 2Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. 3Biological and Biomedical Sciences Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. (1)
Center of Growth Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, China. (1)
Centre for medicines discovery, University of Oxford (1)
Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. (1)
Department of Laboratory Medicine, Institute of Biomedicine, University of Gothenburg, and 2Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden (1)
Department of Laboratory Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden (1)
Institut für Experimentelle Pharmakologie und Toxikologie (1)
Institute of Plant and Microbial Biology (1)
Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI, USA Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI, USA (1)
Max Planck Institute of Biophysics, Frankfurt am Main, Germany (1)
Molecular Skeletal Biology Laboratory, Department of Trauma, Hand and Reconstructive Surgery, University-Medical Center Hamburg-Eppendorf, Hamburg, Germany. (1)
Northwestern University Proteomics Core (1)
Professor of Biochemistry, University of Manchester, UK. Director, Wellcome Trust Centre for Cell-Matrix Research. Director, Cellular & Developmental Systems Domain, Faculty of Biology, Medicine and Health, University of Manchester (1)
Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC) (1)
School of Bioengineering Medicine, Beihang University, Beijing 100191, China (1)
The University of Chicago Medicine Comprehensive Cancer Center, University of Chicago, Chicago, IL USA Department of Pathology Department of Pediatrics Committee on Cancer Biology (1)
University of Colorado School of Medicine Biochemistry and Molecular Genetics Denver, CO (1)

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Variation in homeodomain DNA-binding revealed by high-resolution analysis of sequence preferences

Most homeodomains are unique within a genome, yet many are highly conserved across vast evolutionary distances, implying strong selection on their precise DNA-binding specificities. We determined the binding preferences of the majority (168) of mouse homeodomains to all possible 8-base sequences, re...

ORGANISM(S): Mus musculus

2010-06-26 | E-GEOD-11239 | biostudies-arrayexpress

Required Enhancer: Matrin-3 Structure Interactions for Homeodomain Transcription Programs

Study of the POU-homeodomain transcription factor, has revealed that, binding of Pit1-occupied enhancers to a nuclear matrin-3-rich network/architecture is a key event in effective activation of the Pit1-regulated enhancer / coding gene transcriptional program. All ChIP-seq(s) were designed to under...

ORGANISM(S): Rattus norvegicus

2014-08-03 | E-GEOD-58009 | biostudies-arrayexpress

Homeodomain dependent gene expression in HOX transformed primary cells

The gene expression profile was determined in primary cells transformed by two different HOX genes (HOXA1 and HOXA9) and by two HOX derivatives where the homeodomain was exchanged.

ORGANISM(S): Mus musculus

2013-01-31 | E-MEXP-3617 | biostudies-arrayexpress

Transcription profiling of mouse control embryos and pbx2-MO;pbx4-MO embryos at 10 somites and at 18 somites.

Pbx homeodomain proteins have been implicated in the regulation of gene expression during muscle development. Whether Pbx proteins are required broadly for the regulation of muscle gene expression or are required for the expression of a specific subset of muscle gene expression is not known. We em...

ORGANISM(S): Danio rerio

2008-06-16 | E-GEOD-8428 | biostudies-arrayexpress

Homeodomain-like domain of Plasmodium berghei HDP1 binds to TGCACA motif.

PRJNA1078229 | ENA

High-througput Bacteria one hybrid (B1H) selections for all Drosophila homeodomain proteins

In many metazons, such as humans and Drosophila, homeodomain proteins comprise the second largest family of sequence specific transcription factors. In Drosophila, homeodomains play an important role in development. Many homeodomain proteins display a high level of homology across metazons, presum...

ORGANISM(S): Drosophila melanogaster

2010-11-13 | E-GEOD-25312 | biostudies-arrayexpress

Expression data from Shox2 knockout and wildtype right atria of E11.5 mouse hearts

The heartM-bM-^@M-^Ys rhythm is initiated and regulated by a group of specialized cells in the sinoatrial node (SAN), the primary pacemaker of the heart. Abnormalities in the development of the SAN can result in irregular heart rates (arrhythmias). Although several of the critical genes important fo...

ORGANISM(S): Mus musculus

2013-06-03 | E-GEOD-39924 | biostudies-arrayexpress

Transcription profiling of Arabidopsis homeodomain 2 trichomes

Transcriptional profiling of isolated homeodomain 2 (hd2) trichomes

ORGANISM(S): Arabidopsis thaliana

2009-02-04 | E-MEXP-2022 | biostudies-arrayexpress

HOMEODOMAIN-LIKE shapes chromatin architecture and rewires leaf epidermal patterns [ChIPseq]

PRJNA1248993 | ENA

HOMEODOMAIN-LIKE shapes chromatin architecture and rewires leaf epidermal patterns [ATACseq]

PRJNA1248992 | ENA