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MetabolomicsMetabolic study of BRCA1 knockout cells and WT cells in homo sapiens

BRCA1 mutations are a hallmark of hereditary ovarian cancer, strongly linked to deficiencies in homologous recombination (HR) DNA repair and impaired DNA replication fork protection. However, its roles in cancer progression beyond maintaining genomic integrity remain poorly understood. Through me...

2026-05-15 | MTBLS12245 | MetaboLights
TranscriptomicsExpression analysis of gene expression changes in Homo sapiens SGC-7901 cells after knock down of MTA2 or overexpression of SNHG5
Expression analysis of gene expression changes in Homo sapiens SGC-7901 cells after knock down of MTA2 (Metastasis-associated protein) or overexpression SNHG5 (snoRNA host gene 5) Investigation of whole genome gene expression level changes in a Homo sapiens gastric carcinoma cells SGC-7901 after kno...
ORGANISM(S): Homo sapiens 
2015-09-09 | E-GEOD-65915 | biostudies-arrayexpress
MetabolomicsThe Human Saliva Metabolome
Saliva is composed of a variety of molecules that modulate the oral cavity. It is mainly composed of water (95%) and several minor components such as electrolytes, proteins, and low molecular weight compounds. It consists of metabolites from drinks, foods, drugs, environmental contaminants, and bact...
2015-09-01 | MTBLS100 | MetaboLights
TranscriptomicsModeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees
Understanding evolutionary mechanisms underlying expansion and reorganization of the human brain represents an important aspect in analyzing the emergence of cognitive abilities typical of our species. Comparative analyses of neuronal phenotypes in closest living relatives (Pan troglodytes; the comm...
ORGANISM(S): Pan troglodytes 
2016-08-07 | E-GEOD-83638 | biostudies-arrayexpress
TranscriptomicsRNA-seq of of human (Homo sapiens), gorilla (Gorilla gorilla) and cynomolgus macaque (Macaca fascicularis) iPSC and iPSC-derived NPC cell lines
RNA-seq samples from 3 species across a differentiation from induced pluripotent stem cells to neural progenitor cells were generated to study gene expression evolution. Briefly, previously generated urinary stem cell derived iPSCs of 3 human (Homo sapiens) individuals (3 clones), 1 gorilla (Gorill...
ORGANISM(S): Homo sapiens 
2023-11-23 | E-MTAB-13494 | biostudies-arrayexpress
MetabolomicsUnexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood fraction)
Metabolomics, a new branch of chemical biology, provides compositional and quantitative information about the state of organism or cell at the levels of metabolite constituents. We here report non-targeted metabolome of human blood that is made up of plasma and red blood cells (RBCs), using liquid-c...
2014-07-08 | MTBLS87 | MetaboLights
MetabolomicsTwo-Channel Chemical Isotope Labeling Metabolomics Analysis of Human Fecal Samples

Global metabolomics study of the amine and carboxyl submetabolomes of 16 human fecal samples.

2026-09-23 | MTBLS13531 | MetaboLights
MetabolomicsMetabolomics of the human aqueous humor
Introduction: The optical elements of the eye – cornea, lens, and vitreous humor – are avascular tissues, and their nutrition and waste removal are provided by aqueous humor (AH). The AH production occurs through the active secretion and the passive diffusion/ultrafiltration of blood plasma. The com...
2017-11-06 | MTBLS386 | MetaboLights
TranscriptomicsATAC-seq of human (Homo sapiens) and cynomolgus macaque (Macaca fascicularis) iPSC and iPSC-derived NPC cell lines
ATAC-seq samples from 2 species and 2 cell types were generated to study cis-regulatory element evolution. Briefly, previously generated urinary stem cell derived iPS-cells (Homo sapiens) of 2 human individuals and fibroblast derived cynomolgus macaque iPSCs (Macaca fascicularis) of 2 individuals (...
ORGANISM(S): Macaca fascicularis 
2023-10-25 | E-MTAB-13373 | biostudies-arrayexpress
MetabolomicsThe HuMet Repository: Watching human metabolism at work
Metabolism oscillates between catabolic and anabolic states depending on food intake, exercise, or stresses that change a multitude of metabolic pathways simultaneously. We present the HuMet Repository for exploring dynamic metabolic responses to oral glucose/lipid loads, mixed meals, 36-h fasting, ...
2024-07-23 | MTBLS89 | MetaboLights
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