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GenomicsA Probabilistic Model of Transcription Dynamics applied to Estrogen Signalling in Breast Cancer Cells
Gene transcription mediated by RNA polymerase II (pol-II) is a key step in gene expression. The dynamics of pol-II moving along the transcribed region influences the rate and timing of gene expression. In this work we present a probabilistic model of transcription dynamics which is f...
ORGANISM(S): Homo sapiens 
2014-05-19 | E-GEOD-44800 | biostudies-arrayexpress
UnknownGenome-wide modelling of transcription kinetics reveals patterns of RNA processing delays
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-62789 | biostudies-other
GenomicsGenome-wide modelling of transcription kinetics reveals patterns of RNA processing delays
We descrive a joint model of transcriptional activation and mRNA accumulation, using estrogen receptor ERM-NM-1 activation in MCF-7 breast cancer cell line, which can be used for inference of transcription rate, RNA processing delay and degradation rate given data from high-throughput sequencing tim...
ORGANISM(S): Homo sapiens 
2015-03-04 | E-GEOD-62789 | biostudies-arrayexpress
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