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TranscriptomicsRNA sequencing comparing SCN CSF3R-d715 RUNX1-D171N (RHD) treated with the HDAC inhibitor MS275, octyl-(R)-2hydroxyglutarate (2HG) or solvent control (DMSO)
Effects of TET2 on repressing inflammation have been assigned to its methylcytosine dioxygenase activity, but also to its ability to recruit HDAC-mediated repressor activity to pro-inflammatory genes. To discriminate between the two above-proposed functions of TET2, we asked how inhibition of its en...
ORGANISM(S): Homo sapiens 
2020-08-24 | E-MTAB-9374 | biostudies-arrayexpress
TranscriptomicsGene expression profiling or ERCC1 deficient and control mouse lineage negative bone marrow cells
Transcriptome differences induced by ERCC1 deficiency.
ORGANISM(S): Mus musculus 
2015-04-09 | E-MTAB-3297 | biostudies-arrayexpress
TranscriptomicsMiRNA expression profiling or ERCC1 deficient and control mouse lineage negative, ScaI positive, Kit positive (LSK) bone marrow cells
MiRNA expression differences induced by ERCC1 deficiency.
ORGANISM(S): Mus musculus 
2015-04-09 | E-MTAB-3310 | biostudies-arrayexpress
TranscriptomicsMiRNA expression profiling or ERCC1 deficient and control mouse lineage negative bone marrow cells
MiRNA expression differences induced by ERCC1 deficiency.
ORGANISM(S): Mus musculus 
2015-04-09 | E-MTAB-3298 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse small intestinal CCR6+ group3 innate lymphoid cells
CCR6+NKp46- ILC3 were isolated from the small intestine of untreated mice by flow cytometry. ILC3 from 3 mice were pooled for subsequent RNA sequencing.
ORGANISM(S): Mus musculus 
2019-10-11 | E-MTAB-8387 | biostudies-arrayexpress
TranscriptomicsMouse E11 WT and GATA2 heterozygous HSPCs
Transcriptome analysis from WT and Gata2 heterozygous mouse HSPCs at E11
ORGANISM(S): Mus musculus 
2023-02-17 | E-MTAB-12571 | biostudies-arrayexpress
TranscriptomicsGroup 3 innate lymphoid cells amplify YAP1-driven small intestinal repair
Ror gamma t-deficient mice lack group 3 Innate Lymphoid Cells (ILC3s) and as a result have increased tissue damage and diminished tissue repair in response to insult. To identify repair programs associated with ILC3 presence the transcriptomes of small intestinal stem cells exposed to damage in the ...
ORGANISM(S): Mus musculus 
2018-06-29 | E-MTAB-6639 | biostudies-arrayexpress
TranscriptomicsHeterozygous Gata2b versus wildtype Gata2b zebrafish embryo HSPC CD41
Comparison between wildtype and Gata2b heterozygous zebrafish HSPCs
ORGANISM(S): Danio rerio 
2023-02-17 | E-MTAB-12577 | biostudies-arrayexpress
Genomicsena-DATASET-DKFZ-HIPO-01-12-2017-12:36:36:554-60 - samples
The data set contains bam files aligned using bwa-0.7.8 mem -t 8 -R.
EGAD00001003827 | EGA
TranscriptomicsGene expression profiling on Osx::GFP cells from bone cell suspensions of OCS mice
Oncogenic signaling of the niche can have a severe effect on the hematopoietic compartment and could contribute or play an active role during the development of human leukemia predisposition syndromes. To provide insights into the mechanisms that underlie this concept, as well as their relevance to ...
ORGANISM(S): Mus musculus 
2016-09-22 | E-MTAB-5023 | biostudies-arrayexpress
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