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This is the genome-scale metabolic network of a hepatocyte described in the article: HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology. Gille C, Bölling C, Hoppe A, Bulik S, Hoffmann S, Hübner K, Karlstä...
2005-01-01 | MODEL1009150000 | BioModels
Sirtuins, a family of histone deacetylases, have a fiercely debated role in regulating lifespan of different species. Contrasting recent observations, we here find that overexpression of sir-2.1, the orthologue of mammalian SirT1, does extend C. elegans lifespan. Sirtuins are known to convert NAD+ i...
ORGANISM(S): Caenorhabditis elegans 
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