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MetabolomicsCharacteristics of steroid hormones in systemic lupus erythematosus revealed by GC/MS-based metabolic profiling

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with a remarkable predominance in female, suggesting that steroid hormones may be involved in the pathogenesis. Herein, more than 70 kinds of steroids in urine were detected by gas chromatography/mass spectrometry (GC/MS) to reve...

2023-07-28 | MTBLS7766 | MetaboLights
MetabolomicsHormones & Cognition/Aging/Placebo
Not available
ORGANISM(S): Homo sapiens 
ST000814 | MetabolomicsWorkbench
MetabolomicsDistinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones

INTRODUCTION: Prostatitis is likely to occur in younger or middle-aged men, while prostate cancer is likely to occur in older men. Although amino acids and lipids as biomarkers of prostate cancer have been examined using prostate cancer cell lines/tissues, no previous studies hav...

2020-11-04 | MTBLS2028 | MetaboLights
TranscriptomicsSingle cell RNA Sequencing (scRNA-Seq) on human embryonic stem cell-derived thyroid organoids exposed for 3 days to sex hormones + 1 day to benzo[a]pyrene (BaP) or PCB153
Human embryonic stem cell-derived thyroid follicles were exposed for 3 days to a mixture of the sex hormones beta-estradiol (E2), 5-alpha-dihydrotestosterone (DHT) and progesterone (PG) that resemble the serum levels of human male and female (post-ovulation) of reproductive age. Afterwards, they wer...
ORGANISM(S): Homo sapiens 
2024-08-29 | E-MTAB-13502 | biostudies-arrayexpress
ProteomicsSILAC-Based Proteomics of Primary Human Kidney Cells treated with Sex Hormones.
Male sex predispose to many kidney diseases. Considering that androgens exert deleterious effects in a variety of cell types within kidney, we hypothesized that dihydrotestosterone (DHT) would impair the biology of the renal tubular cell by inducing changes in the proteome. We employed stable isotop...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080854 | MassIVE
TranscriptomicsRice global gene expression profile in response to plant hormones
A time course gene expression profiling of rice treated with various plant hormones (abscisic acid, gibberelin, auxin, brassinosteroid, cytokinin and jasmonic acid) was performed to obtain an overall signature of the rice transcriptome in response to each phytohormone. The transcriptome of rice see...
ORGANISM(S): Oryza sativa Japonica Group 
2012-12-03 | E-GEOD-39429 | biostudies-arrayexpress
ProteomicsDiverse peptide hormones affecting root growth identified in the Medicago truncatula secreted peptidome
Multigene families encoding diverse secreted peptide hormones play important roles in plant development. A need exists to efficiently elucidate the structures and post-translational-modifications of these difficult-to-isolate peptide hormones in planta so that their biological functions can be deter...
ORGANISM(S): Medicago truncatula (Barrel medic) (Medicago tribuloides) 
2017-10-31 | PXD007614 | Pride
Medicago truncatula Secretoer peptide hormones Lc-ms/ms 
TranscriptomicsThe AtGenExpress: Basic hormone treatment of seedlings in Arabidopsis
Arabidopsis seedlings of the wild-type or hormone mutants were treated with plant hormones. 72 samples were analyzed by Affymetrix GeneChip, ATH1
ORGANISM(S): Arabidopsis thaliana 
2012-07-16 | E-GEOD-39384 | biostudies-arrayexpress
TranscriptomicsCoordinate Regulation of Metabolites Glycosylation and Stress Hormones Biosynthesis by TT8 in Arabidopsis
Secondary metabolites play a key role in coordinating ecology and defense strategies of plants. Diversity of these metabolites arise by conjugation of core structures with diverse chemical moieties, such as sugars in glycosylation. Active pools of phytohormones, including those involved in plant str...
ORGANISM(S): Arabidopsis thaliana 
2016-07-20 | E-GEOD-59048 | biostudies-arrayexpress
TranscriptomicsIntegrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells
We have found that thyroid hormones (THs), acting as soluble integrin αvβ3 ligands, activate growth-related signaling pathways in T-cell lymphomas (TCL). Specifically, TH-activated αvβ3 integrin signaling promotes TCL proliferation and angiogenesis, in part, via the up-regulation of VEGF. CUTLL1 cel...
ORGANISM(S): Homo sapiens 
2015-02-18 | E-GEOD-63122 | biostudies-arrayexpress
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