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TranscriptomicsGene expression of whole hippocampus 24hr post-injury in rat
Traumatic brain injury (TBI) alters and dysregulates the expression of thousands of genes in the brain. Since some of the most common problems in TBI patients are learning and memory deficits, we are studying the effects of TBI on the hippocampus, a region of the brain which is essential for learnin...
ORGANISM(S): Rattus norvegicus 
2015-01-08 | E-GEOD-59645 | biostudies-arrayexpress
GenomicsMolecular Genetic Studies of Developmental Brain Disorders

Study 1
2R01-NS050375 (PI: DOBYNS, William B.)
The genetic basis of mid-hindbrain malformations
Our general goal for this project is to advance our understanding of human developmental disorders that involve the brainstem and cerebellum - brain structures derived from the embryoni...

phs000455.v1.p1 | EGA
TranscriptomicsCommon molecular signature of two neuroprotective agents
The current lack of proven pharmacological treatment options for traumatic brain injury (TBI) patients reflects the poor translation of successful preclinical studies in clinical trials. This may be due to poor choice of therapeutic agents based on incomplete knowledge of critical elements of neurop...
ORGANISM(S): Rattus norvegicus 
2012-12-23 | E-GEOD-31357 | biostudies-arrayexpress
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