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TranscriptomicsAnalysis of Unannotated Equine Transcripts Identified by mRNA Sequencing
Horse-specific genes are not readily identified from available equine EST/cDNA resources due to relatively limited coverage. In addition, equine gene sets predicted in silico by Ensembl and NCBI will not identify horse specific genes since they rely on homology-based projection of gene structure ann...
ORGANISM(S): Equus caballus 
2013-07-30 | E-GEOD-46858 | biostudies-arrayexpress
TranscriptomicsGene expression variation in horse placental and fetal tissue, and resting and stimulated horse lymphocytes
This SuperSeries is composed of the following subset Series: GSE35741: Gene expression variation in horse placental and fetal tissue, and resting and stimulated horse lymphocytes [Agilent-018932] GSE35742: Gene expression variation in horse placental tissue, and resting and stimulated horse lymphocy...
ORGANISM(S): Equus caballus 
2012-02-14 | E-GEOD-35743 | biostudies-arrayexpress
TranscriptomicsGene expression variation in horse placental tissue, and resting and stimulated horse lymphocytes [Agilent-021322]
We undertook gene expression microarray experiments to identify genes that are differentially expressed in invasive (Chorionic Girdle) and non-invasive (Chorion) placental tissue, and resting and Pokeweed Mitogen (PWM) stimulated horse lymphocytes. Conceptus tissues were dissected to obtain chorion...
ORGANISM(S): Equus caballus 
2012-02-14 | E-GEOD-35742 | biostudies-arrayexpress
ProteomicsData in support of the equine mesenchymal stem cell surface proteome for mining for new surface markers
Regenerative medicine in aims to restore structure and function to tissues or organs damaged by time, disease or injury. Stem cells have great potential for tissue repair and regeneration, why they are intensely investigated in equine clinical research. However, before any type of stem cell can be a...
ORGANISM(S): Equus caballus (Horse) 
2018-11-04 | PXD008884 | Pride
Horse stem cells membrane 
TranscriptomicsGene expression variation in horse placental and fetal tissue, and resting and stimulated horse lymphocytes [Agilent-018932]
We undertook gene expression microarray experiments to identify genes that are differentially expressed in different placental and fetal tissue, and resting and Pokeweed Mitogen (PWM) stimulated horse lymphocytes. Conceptus tissues were dissected to obtain chorionic girdle, chorion, and fetal tissu...
ORGANISM(S): Equus caballus 
2012-02-14 | E-GEOD-35741 | biostudies-arrayexpress
TranscriptomicsStallion sperm transcriptome as revealed by microarray analysis and RNA sequencing
Purpose: In order to understand the functional significance of sperm transcriptome in stallion fertility, the aim of this study was to generate a detailed body of knowledge about the sperm RNA profile that defines a normal fertile stallion. Methods: The 50 bp single-end ABI SOLiD raw reads were dire...
ORGANISM(S): Equus caballus 
2013-02-19 | E-GEOD-38725 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression changes during the estrous cycle in equine endometrium
The equine endometrium exhibits characteristic morphological and functional changes during the estrous cycle controlled by the interplay of progesterone and estradiol. A microarray analysis of endometrial tissue samples derived from 5 time points of the estrous cycle (D0, D3, D8, D12, and D16) was p...
ORGANISM(S): Equus caballus 
2012-10-23 | E-GEOD-39043 | biostudies-arrayexpress
GenomicsDNA methylation in mammalian placentas
Over the last 20-80 million years the mammalian placenta has taken on a variety of morphologies through both divergent and convergent evolution. Recently we have shown that the human placenta genome has a unique epigenetic pattern of large partially methylated domains (PMDs) and highly methylation ...
ORGANISM(S): Monodelphis domestica 
2015-08-05 | E-GEOD-63330 | biostudies-arrayexpress
TranscriptomicsChanges in gene expression during acinar morphogenesis of normal-like human mammary epithelial cells in a 3D basement membrane cultures
In this study, we examined temporal changes in gene expression during acinar morphogenesis of normal-like human mammary epithelial cells (MCF-10A) in a three-dimensional (3D) basement membrane cultures. Changes in gene expression in 3D culture of MCF-10A cells were measured at 4, 8, and 12 days.
ORGANISM(S): Homo sapiens 
2013-12-01 | E-GEOD-33354 | biostudies-arrayexpress
ProteomicsThe combined action of suicide gene exosomes from pancreatic cancer-associated fibroblasts and from mesenchymal stem cells as a pancreatic ductal adenocarcinoma treatment approach
Exosomes from pancreatic cancer-associated fibroblasts and mesenchymal stem cells that have been transduced with the yeast cytosine deaminase::uracil phosphoribosyl transferase release suicide gene exosomes acting as "Trojan horse" drugs, effectively killing pancreatic cancer cells by converting the...
ORGANISM(S): Homo sapiens (Human) 
2025-08-08 | PXD059055 | Pride
Pancreatic cancer-associated fibroblasts Mesenchymal stem cells Gene-directed enzyme prodrug therapy Pancreatic cancer intracellular treatment Suicide gene exosomes 
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