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MetabolomicsDiel metabolomics analysis of a hot spring chlorophototrophic microbial mat leads to new hypotheses of community member metabolisms
Dynamic environmental factors such as light, nutrients, salt, and temperature continuously affect chlorophototrophic microbial mats, requiring adaptive and acclimative responses to stabilize composition and function. Quantitative metabolomics analysis can provide insights into metabolite dynamics fo...
2024-02-23 | MTBLS187 | MetaboLights
UnknownMolecular level study of hot water extracted green tea buried in soils - a proxy for labile soil organic matter.
Not available
S-EPMC6992787 | biostudies-literature
TranscriptomicsArabidopsis plants exposed to combined heat and drought stress
One of the eminent opportunities afforded by modern genomic technologies is the potential to provide a mechanistic understanding of the processes by which genetic change translates to phenotypic variation and the resultant appearance of distinct physiological traits. Indeed much progress has been m...
ORGANISM(S): Arabidopsis thaliana 
2010-05-26 | E-GEOD-9415 | biostudies-arrayexpress
TranscriptomicsComparative transcriptional profiling of rice undergoing infection by X. oryzae pv. oryzae or by X. oryzae pv. oryzicola
RESEARCH SUMMARY Bacterial blight and bacterial leaf streak, two of the most serious diseases of rice, are caused by Xanthomonas oryzae pathovar (pv.) oryzae (Xoo) and X. oryzae pv. oryzicola (Xoc) respectively. Xoo is a vascular pathogen that invades the xylem, whereas Xoc is non-vascular and c...
ORGANISM(S): Oryza sativa 
2009-06-24 | E-GEOD-16793 | biostudies-arrayexpress
TranscriptomicsNOD2 transmissible microbiota predispose WT mice to inflammation
Instability in the composition of gut bacterial communities, referred as dysbiosis, has been associated with important human intestinal disorders such as Crohn’s disease and colorectal cancer. Our data showed that Nod2-mediated risk of intestinal inflammation in colitis model is communicable to WT m...
ORGANISM(S): Mus musculus 
2013-01-02 | E-GEOD-36481 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA and B cell receptor profiling of B cell response to SARS-CoV-2 vaccination
We generated single-cell transcriptomic and BCR sequencing data of B cells from peripheral blood samples taken from a SARS-CoV-2-antigen-naive cohort being vaccinated with the SARS-CoV-2 mRNA-1273 vaccine. Blood samples were collected at the baseline timepoint D-1 (i.e. one day prior to the initial ...
ORGANISM(S): Homo sapiens 
2026-05-08 | E-MTAB-16531 | biostudies-arrayexpress
TranscriptomicsNOD2-dependent licensing of the microbiota predispose to transmissible inflammation and tumorigenesis in the colon.
Instability in the composition of gut bacterial communities, referred as dysbiosis, has been associated with important human intestinal disorders such as CrohnM-bM-^@M-^Ys disease and colorectal cancer. Here, we show that dysbiosis coupled to Nod2 or Rip2 deficiency suffices to cause an increased ri...
ORGANISM(S): Mus musculus 
2013-01-02 | E-GEOD-32421 | biostudies-arrayexpress
UnknownThe pace of change of summertime temperature extremes.
Not available
S-EPMC11494304 | biostudies-literature
TranscriptomicsDynamics of Nitrogen-regulated Gene Expression Reveals a Reciprocal Relationship between Cell Growth Rate and Nitrogen Catabolism
Cell growth rate is regulated in response to resource availability including the abundance, and molecular form, of essential nutrients. In the model eukaryotic cell, Saccharomyces cerevisiae (budding yeast), the molecular form of environmental nitrogen impacts both cell growth rate and mRNA express...
ORGANISM(S): Saccharomyces cerevisiae 
2014-05-05 | E-GEOD-57293 | biostudies-arrayexpress
TranscriptomicsAMPK governs lineage specification through Tfeb-dependent regulation of lysosomes
Faithful execution of developmental programs relies on the acquisition of unique cell identities from pluripotent progenitors, a process governed by combinatorial inputs from numerous signaling cascades that ultimately dictate lineage-specific transcriptional outputs. Despite growing evidence that m...
ORGANISM(S): Mus musculus 
2016-03-09 | E-GEOD-77705 | biostudies-arrayexpress
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