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TranscriptomicssmRNA sequencing analysis to identify p53-dependent non-coding RNA networks in Chronic Lymphocytic Leukemia
Mutations of the tumor suppressor p53 lead to chemotherapy resistance and a dismal prognosis in chronic lymphocytic leukemia (CLL). Comparing miRNA/non-coding RNA expression profiles between p53 wild-type and p53 mutant samples in response to DNA damage, we exploit the impaired transcriptional activ...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-66186 | biostudies-arrayexpress
UnknownKetone body oxidation increases cardiac endothelial cell proliferation
Blood vessel formation is dependent on metabolic adaption in endothelial cells. Glucose and fatty acids are essential substrates for ATP and biomass production, however, the metabolism of other substrates remains poorly understood. Ketone bodies are important nutrients for cardiomyocytes during star...
S-SCDT-EMM-2021-14753 | biostudies-other
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