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TranscriptomicsNeuropeptides:developmental signals in placode progenitor formation
Few families of signaling factors have been implicated in the control of development. Here we identify the neuropeptides nociceptin and somatostatin, a neurotransmitter and neuroendocrine hormone, as a class of developmental signals in chick and zebrafish. We show that signals from the anterior mese...
ORGANISM(S): Gallus gallus 
2014-04-25 | E-GEOD-48116 | biostudies-arrayexpress
TranscriptomicsTotal RNAseq of sfpq sibling (+/+, +/-) and null (-/-) primary zebrafish neuron cellular and neurite tissue
Zebrafish primary neurons either sfpq sibling/control (+/+, +/-) or null (-/-) were cultured in transwell inserts. At DIV2, for each genotype, cellular and neurite tissues were separately isolated, RNA extracted and total RNAseq performed.
ORGANISM(S): Danio rerio 
2022-02-19 | E-MTAB-11431 | biostudies-arrayexpress
TranscriptomicsRNA-seq of snrnp70 mutant zebrafish and its rescue by overexpression of cytoplasmic SNRNP70
It has been recently shown that SNRNP70, a major component of the spliceosome, as well as other splicing regulators are found in axons. To investigate the role of SNRNP70 in axons, we generated a zebrafish null mutant and found motor connectivity defects that can be partially rescued upon transgenic...
ORGANISM(S): Danio rerio 
2022-10-31 | E-MTAB-12301 | biostudies-arrayexpress
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