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GenomicsBase-resolution analyses of parent-of-origin and sequence dependent allele specific DNA methylation in the mouse genome (MRE-seq)
Allele specific DNA methylation (ASM) is crucial for genomic imprinting and mammalian development. Here we present a base-resolution, genome-wide allelic DNA methylation map for both CG and non-CG sites in the mouse brain. We found parent-of-origin dependent (imprinted) ASM at 1,952 CGs which form 5...
ORGANISM(S): Homo sapiens 
2012-02-15 | E-GEOD-33579 | biostudies-arrayexpress
TranscriptomicsBase-resolution analyses of parent-of-origin and sequence dependent allele specific DNA methylation in the mouse genome (RNA-seq)
Allele specific DNA methylation (ASM) is crucial for genomic imprinting and mammalian development. Here we present a base-resolution, genome-wide allelic DNA methylation map for both CG and non-CG sites in the mouse brain. We found parent-of-origin dependent (imprinted) ASM at 1,952 CGs which form 5...
ORGANISM(S): Mus musculus 
2012-02-15 | E-GEOD-33468 | biostudies-arrayexpress
ProteomicsRat Bronchoalveolar Lavage Proteome Changes Following E-cigarette Aerosol Exposures
Label free quantitative proteomics of bronchoalveolar lavage (BAL) fluid collected from rats exposed to e-cigarette aerosols (humidified air control, PG/VG, PG/VG + Nicotine, or PG/VG + Nicotine + Vanillin)
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2023-01-06 | MSV000091015 | MassIVE
TranscriptomicsThe role of HIF in FH-associated renal neoplasia
Fumarate hydratase (FH) mutations predispose to renal cysts cancer. These cancers overexpress hypoxia-inducible factor-alpha (Hif-1a). We have generated a conditional Fh1 (mouse FH) knockout mice that develop renal cysts and overexpress Hif-1a. In order to identify the contribution of Hif-1a to cyst...
ORGANISM(S): Mus musculus 
2011-10-23 | E-GEOD-29988 | biostudies-arrayexpress
TranscriptomicsEffect of ultradian light-dark cycles on the transcriptome of mice carying a human Per3 polymorphism
In humans, a primate-specific variable-number tandem-repeat (VNTR) polymorphism (4 or 5 repeats 54 nt in length) in the circadian gene PER3 is associated with differences in sleep timing and homeostatic responses to sleep loss. We investigated the effects of this polymorphism on circadian rhythmicit...
ORGANISM(S): Mus musculus 
2014-03-11 | E-GEOD-55495 | biostudies-arrayexpress
TranscriptomicsEffect of 12 hour sleep restriction on the transcriptome of mice carying a human Per3 polymorphism
In humans, a primate-specific variable-number tandem-repeat (VNTR) polymorphism (4 or 5 repeats 54 nt in length) in the circadian gene PER3 is associated with differences in sleep timing and homeostatic responses to sleep loss. We investigated the effects of this polymorphism on circadian rhythmicit...
ORGANISM(S): Mus musculus 
2014-03-11 | E-GEOD-55494 | biostudies-arrayexpress
ProteomicsCD81 facilitates tumor cell clustering and metastasis in triple negative breast cancer
Tumor-initiating cells with reprogramming plasticity and/or de-differentiation attributes have been thought to initiate primary tumor development as well as to regenerate secondary tumors in metastatic organs; however, the molecular mechanisms are not fully understood. We previously found that breas...
ORGANISM(S): Homo Sapiens (human) 
2022-10-18 | PXD029529 | JPOST Repository
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