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GenomicsA GWAS in uveal melanoma identifies risk polymorphisms in the CLPTM1L locus.
Uveal melanoma, a rare malignant tumor of the eye, is predominantly observed in populations of European ancestry. A genome-wide association study of 259 uveal melanoma patients compared to 401 controls all of European ancestry revealed a candidate locus at chromosome 5p15.33 (region rs421284: OR = 1...
EGAS00001002334 | EGA
GenomicsUM_GWAS
Genotype cases using Illumina HumanOmni5
EGAD00010001463 | EGA
GenomicsData Access Committee for Institut Curie
Data Access Committee EGAC00001000670
EGAC00001000670 | EGA
Genomics8044f1ed-f7ee-42e5-87e3-6506d5746d96 - samples
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Despite improvement of diagnosis and treatment of the primary tumor, there is no effective treatment of metastatic disease and approximately half of patients will die within one year or less following metastases detecti...
EGAD00001004554 | EGA
GenomicsComprehensive genetic analysis of uveal melanoma heterogeneity during metastatic progression
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Despite improvement of diagnosis and treatment of the primary tumor, there is no effective treatment of metastatic disease and approximately half of patients will die within one year or less following metastases detecti...
EGAS00001002761 | EGA
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