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UnknownReduced Neutrophil Extracellular Trap (NET) Formation During Systemic Inflammation in Mice With Menkes Disease and Wilson Disease: Copper Requirement for NET Release.
Not available
S-EPMC6974625 | biostudies-literature
UnknownMolecular dynamics of water-mediated interactions of a linear benzimidazole-biphenyl diamidine with the DNA minor groove.
Not available
S-EPMC2698132 | biostudies-literature
TranscriptomicsGenome-scale analysis in blood progenitor and mast cells reveals how lineage-affiliated transcription factors control distinct regulatory programs [Beadchip Experiments]
Despite major advances in the generation of genome-wide binding maps, the mechanisms by which transcription factors (TFs) regulate cell type identity have remained largely obscure. Through comparative analysis of 10 key haematopoietic TFs in both mast cells and blood progenitors, we demonstrate that...
ORGANISM(S): Mus musculus 
2014-04-24 | E-GEOD-47988 | biostudies-arrayexpress
TranscriptomicsGenome-scale analysis in blood progenitor and mast cells reveals how lineage-affiliated transcription factors control distinct regulatory programs [Beadchip Experiments #2]
Despite major advances in the generation of genome-wide binding maps, the mechanisms by which transcription factors (TFs) regulate cell type identity have remained largely obscure. Through comparative analysis of 10 key haematopoietic TFs in both mast cells and blood progenitors, we demonstrate that...
ORGANISM(S): Mus musculus 
2014-04-24 | E-GEOD-55244 | biostudies-arrayexpress
TranscriptomicsGenome-scale analysis in blood progenitor and mast cells reveals how lineage-affiliated transcription factors control distinct regulatory programs
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-04-24 | E-GEOD-48086 | biostudies-arrayexpress
ProteomicsFeeling hot headed: Quantitative proteomic profiling reveals region specific brain responses to elevated water temperature in Atlantic salmon (Salmo salar L.)
Increasing summer seawater temperatures in Tasmania pose a significant challenge to Atlantic salmon aquaculture. While several studies have investigated the physiological impacts of thermal stress, the molecular mechanisms underlying brain-region-specific adaptation remain unexplored. Understanding ...
ORGANISM(S): Salmo salar (Atlantic salmon) 
2026-09-14 | PXD070727 | Pride
Proteomics Atlantic salmon Brain regions Elevated temperature 
GenomicsA fully validated blood stem/progenitor cell regulatory network reveals mechanisms of cell state stabilisation
The aim of this study was to determine the genomic binding sites of important haematopoietic transcription factors in haematopoietic cell lines. 416Bs cells were fixed with either 1 or 0.4 % formaldehyde for 10 mins. Chromatin was isolated, sonicated for 7 mins (30 sec on, 30 sec off), and specific ...
ORGANISM(S): Mus musculus 
2016-03-17 | E-GEOD-69776 | biostudies-arrayexpress
ProteomicsSILAC-Based Proteomics of Primary Human Kidney Cells treated with Sex Hormones.
Male sex predispose to many kidney diseases. Considering that androgens exert deleterious effects in a variety of cell types within kidney, we hypothesized that dihydrotestosterone (DHT) would impair the biology of the renal tubular cell by inducing changes in the proteome. We employed stable isotop...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080854 | MassIVE
UnknownSharing biological data: why, when, and how.
Not available
S-EPMC10390076 | biostudies-literature
TranscriptomicsThe transcriptional program controlled by Runx1 during early hematopoietic development (expression data)
Transcription factors have long been recognised as powerful regulators of mammalian development, yet it is largely unknown how individual key regulators operate within wider regulatory networks. Here we have used a combination of global gene expression and chromatin-immunoprecipitation approaches a...
ORGANISM(S): Mus musculus 
2012-05-29 | E-GEOD-29112 | biostudies-arrayexpress
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