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TranscriptomicsTranscription profiling of skin from wild type and Hoxc13 transgenic mice to investigate their propensity to develop severe hair growth defects and alopecia
A study of the effects of Hoxc13 overexpression in skin using Hoxc13 transgenic mice (GC13) known to develop severe hair growth defects and alopecia. Total skin from GC13 mice 5 dpn is compared to total skin from normal FVB mice 5 dpn using Affymetrix HG-U74Av2 GeneChips.
ORGANISM(S): Mus musculus 
2007-12-04 | E-GEOD-2374 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression profile in skin of Hoxc13 gene-targeted mice
Hoxc13 has been shown to be essential for proper hair shaft differentiation as Hoxc13 gene-targeted (Hoxc13tm1Mrc) mice completely lack external hair. Because of the phenotypic parallels to the Foxn1nu (nude) mutant mice, we tested whether Hoxc13 and Foxn1 act in a common pathway of hair follicle (H...
ORGANISM(S): Mus musculus 
2010-08-25 | E-GEOD-23759 | biostudies-arrayexpress
TranscriptomicsHoxc13 overexpression in skin
A study of the effects of Hoxc13 overexpression in skin using Hoxc13 transgenic mice (GC13) known to develop severe hair growth defects and alopecia. Total skin from GC13 mice 5 dpn is compared to total skin from normal FVB mice 5 dpn using Affymetrix HG-U74Av2 GeneChips. Keywords: repeat sample
ORGANISM(S): Mus musculus 
2006-03-07 | GSE2374 | GEO
UnknownThe inconsistent regulation of HOXC13 on different keratins and the regulation mechanism on HOXC13 in cashmere goat (Capra hircus).
Not available
S-EPMC6107959 | biostudies-literature
TranscriptomicsDifferential gene expression profile in skin of Hoxc13 gene-targeted mice
Hoxc13 has been shown to be essential for proper hair shaft differentiation as Hoxc13 gene-targeted (Hoxc13tm1Mrc) mice completely lack external hair. Because of the phenotypic parallels to the Foxn1nu (nude) mutant mice, we tested whether Hoxc13 and Foxn1 act in a common pathway of hair follicle (H...
ORGANISM(S): Mus musculus 
2010-08-25 | GSE23759 | GEO
GenomicsHuman skin specific long noncoding RNA HOXC13-AS regulates keratinocyte differentiation by inferfering with Golgi-ER retrograde transport
Human skin specific long noncoding RNA HOXC13-AS regulates keratinocyte differentiation by inferfering with Golgi-ER retrograde transport
PRJNA849206 | ENA
TranscriptomicsHuman skin specific long noncoding RNA HOXC13-AS regulates keratinocyte differentiation by inferfering with Golgi-ER retrograde transport
In an RNAseq analysis, we have identified the HOXC13-AS significantly downregulated in wound biopsies and epidermal cells compared to skin counterparts. To study the genes regulated by HOXC13-AS, we transfected HOXC13-AS siRNA pool into human primary epidermal keratinocytes to knockdown HOXC13-AS an...
ORGANISM(S): Homo sapiens 
2022-06-15 | GSE206103 | GEO
UnknownEvolutionary origin of Hoxc13-dependent skin appendages in amphibians.
Not available
S-EPMC10948813 | biostudies-literature
UnknownNaked (N) mutant mice carry a nonsense mutation in the homeobox of Hoxc13.
Not available
S-EPMC11892394 | biostudies-literature
GenomicsMus musculus
Hoxc13 overexpression in skin
PRJNA91529 | ENA
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