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TranscriptomicsMenadione reduces the expression of virulence- and colonisation-associated genes in Helicobacter pylori
Examination of the effect of menadione (final concentration 16 µM) on growth of Helicobacter pylori.
ORGANISM(S): Helicobacter pylori 
2024-11-07 | E-MTAB-14439 | biostudies-arrayexpress
MetabolomicsA data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity
The mechanisms responsible for weight loss-induced improvement in insulin sensitivity are partially understood. Greater insight can now be achieved through deep phenotyping and data integration. Here, we used an integrative approach to investigate associations between changes in insulin sensitivity ...
2021-02-11 | MTBLS653 | MetaboLights
TranscriptomicsFLORINASH - The role of intestinal microflora in non-alcoholic fatty liver disease (NAFLD) EU FP7-HEALTH, project number 241913
FLORINASH - The role of intestinal microflora in non-alcoholic fatty liver disease (NAFLD) EU FP7-HEALTH, project number 241913
Florinash examined the role on the gut microbiota in NAFLD. Metagenomic, proteomic, metabolomic and transcriptomic data were integrated to give provide a systems biology...
ORGANISM(S): Homo sapiens 
2018-03-15 | E-MTAB-4856 | biostudies-arrayexpress
TranscriptomicsEffects of gut-derived trimethylamines on an in vitro model of the blood–brain barrier
The experiment was designed to look at the effect (on gene expression) of exposing human cerebromicrovascular endothelial cell line hCMEC/D3 to trimethylamine (0.4 micromolar) or trimethylamine N-oxide (40 micromolar) for 24 h, to determine if circulating metabolites have the potential to affect int...
ORGANISM(S): Homo sapiens 
2019-10-31 | E-MTAB-6662 | biostudies-arrayexpress
TranscriptomicsDetermination of effects of propionate on gene expression in human cerebromicrovascular endothelial cell line hCMEC/D3
The experiment was designed to look at the effect (on gene expression) of exposing human cerebromicrovascular endothelial cell line hCMEC/D3 to propionate (3 micromolar) for 24 h, to determine if circulating metabolites have the potential to affect integrity of the blood-brain barrier.
ORGANISM(S): Homo sapiens 
2018-03-05 | E-MTAB-5686 | biostudies-arrayexpress
TranscriptomicsComparison of transcriptomes of TamA, TamB and TamAB knock-out strains
Comparison of transcriptomes of TamA, TamB and TamAB knock-out strains.
ORGANISM(S): Pseudomonas aeruginosa UCBPP-PA14 
2025-09-26 | E-MTAB-15348 | biostudies-arrayexpress
MetabolomicsFaecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients

BACKGROUND: The gut-brain axis and the intestinal microbiota are emerging as key players in health and disease. Shifts in intestinal microbiota composition affect a variety of systems, however, evidence of their direct impact on cognitive functions is still lacking. We tested whe...

2021-12-17 | MTBLS1437 | MetaboLights
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