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Higher self renewal and oncogenic potential of keratinocytes from Black versus White populations linked to the hydroxysteroid dehydrogenase HSD17B7 gene [HSD17B7 overexpression]
HSD17B7 is required for Sensory Hair Cells Function by Regulating Cholesterol Synthesis
Cholesterol homeostasis is fundamental to cellular function, and its disruption underlies a wide range of human diseases. However, the contribution of cholesterol biosynthesis to auditory physiology remains poorly understood. HSD17B7 (17β-Hydroxysteroid dehydrogenase type 7) catalyzes the conversion...
ORGANISM(S): Danio rerio 
2026-04-29 | GSE319132 | GEO
Transcriptomic profiling of 3 human keratinocytes strains with HSD17B7 overexpression.
ORGANISM(S): Homo sapiens 
2021-05-12 | GSE172288 | GEO
Dysregulation of estrogen signaling and HSD17B7 in the prostate stroma of African American men
African American men experience a higher incidence and severity of prostate cancer relative to European American men, and there is a range of risk factors that may contribute to this disparity. Prostate adenocarcinoma originates from the epithelium, which is significantly influenced by signaling fro...
ORGANISM(S): Homo sapiens 
2026-01-27 | GSE316984 | GEO
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