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Paragemmobacter amnigenus strain:HSP-20 Genome sequencing and assembly
Paragemmobacter amnigenus strain:HSP-20 Genome sequencing and assembly
The wild type (WT) and HSP-1 EEYD (worms generating endogenously mutated HSP-1) C. elegans were cultured under normal conditions (20 degrees) or exposed to 30 degrees for 16 hours as L4 larvae (referred to as heat stress/HS). In WT worms undergoing HS, the activity of CHN-1 ubiquitin ligase is antic...
ORGANISM(S): Caenorhabditis elegans 
2024-11-08 | PXD048200 | Pride
Aeromonas hydrophila strain:Ah-HSP Genome sequencing and assembly
Human PBMCs: Patients with HSPN vs. Patients with HSP
Hereditary Spastic Paraplegia (HSP) leads to progressive gait disturbances with lower limb muscle weakness and spasticity. Mutations in SPG4 are a major cause of autosomal-dominant HSP. Spastin, the protein encoded by SPG4, is a microtubule-severing protein and is enriched in the distal axon of cor...
ORGANISM(S): Homo sapiens 
The endoplasmic reticulum (ER) is an organelle associated with lipid metabolism. However, the involvement of the ER in nutritional status-dependent energy homeostasis is largely unknown. The results of this study demonstrate that IRE-1, an ER protein known to be involved in the unfolded protein resp...
ORGANISM(S): Caenorhabditis elegans 
We used Au nanoparticles (Au-NPs) as a model for studying particle specific effects of manufactured nanomaterials (MNMs) by examining the toxicogenomic responses in a model soil organism, free living nematode Caenorhabditis elegans. Global genome expression for nematodes exposed to 4-nm citrate-coat...
ORGANISM(S): Caenorhabditis elegans 
Physiological interaction partners of the small heat shock protein HSP-17 from C. elegans were to be identified in the context of a study on the function of this non-canonical small heat shock protein in vivo and in vitro. An immunoprecipitation with an antibody raised against HSP-17 was performed o...
ORGANISM(S): Caenorhabditis elegans 
2020-03-23 | PXD016485 | Pride
HSP and CD279 gene expression as candidate biomarkers in symptomatic LGLL patients
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