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TranscriptomicsRsk2 controls synovial fibroblast hyperplasia and the course of arthritis.
To understand differences in the pathogenesis of synovial hyperplasia during TNF-induced arthritis, we compared the global gene expression of hTNFtg and hTNFtg;Rsk2-/y primary synovial fibroblasts. Murine fibroblast-like synoviocytes (FLS) were isolated from the hind paws of hTNFtg and hTNFtg;Rsk2-/...
ORGANISM(S): Mus musculus 
2014-12-04 | E-GEOD-52992 | biostudies-arrayexpress
TranscriptomicsMonocyte vs Macrophage Study
Human intestinal macrophages contribute to tissue homeostasis in noninflamed mucosa through profound down-regulation of pro-inflammatory cytokine release. Here, we show that this down-regulation extends to Toll-like receptor (TLR)-induced cytokine release, as intestinal macrophages expressed TLR3-TL...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-22373 | biostudies-arrayexpress
UnknownImpact of Intensity-Modulated Radiation Therapy Technique for Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the NRG Oncology RTOG 0617 Randomized Clinical Trial.
Not available
S-EPMC5455690 | biostudies-literature
TranscriptomicsJnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis
Hepatic fibrosis is a wound-healing response to chronic liver injury, which may result in cirrhosis and liver failure. The c-Jun N-terminal kinase-1 (JNK1) gene has been shown to be involved in liver fibrosis. Here, we aimed to investigate the molecular mechanism and identify the cell-type involved ...
ORGANISM(S): Mus musculus 
2013-11-27 | E-GEOD-40041 | biostudies-arrayexpress
ProteomicsT.brucei - Whole organism, sequence+MS2 intensity (Urbaniaketal,jproteomeres2013)
abundance based on sequence+MS2 intensity, Interaction consistency score: 17.7, Coverage: 56
ORGANISM(S): 5691 
2013-00-00 | 4092869827 | PAXDB
ProteomicsT.brucei - Whole organism, sequence+MS2 intensity (Urbaniaketal,jproteomeres2013)
abundance based on sequence+MS2 intensity, Interaction consistency score: 17.4, Coverage: 56
ORGANISM(S): 5691 
2013-00-00 | 4181687758 | PAXDB
TranscriptomicsExpression data from rhesus macaque colon, jejunum, and lung
The mucosa that lines the respiratory and gastrointestinal (GI) tracts is an important portal of entry for pathogens and provides the frontline of immune defense against HIV infection. Using the simian immunodeficiency virus (SIV) rhesus macaque model, we have performed a comparative analysis of hos...
ORGANISM(S): Macaca mulatta 
2013-11-01 | E-GEOD-51615 | biostudies-arrayexpress
UnknownThe Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
Not available
S-EPMC6075733 | biostudies-literature
UnknownBrown Adipose Tissue: Multimodality Evaluation by PET, MRI, Infrared Thermography, and Whole-Body Calorimetry (TACTICAL-II).
Not available
S-EPMC6899540 | biostudies-literature
UnknownDiagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study.
Not available
S-EPMC4575273 | biostudies-literature
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