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TranscriptomicsThe identification of differentially expressed genes between animal and vegetal blastomeres in Xenopus laevis
To identify asymmetrically localized maternal mRNAs along the animal-vegetal axis in cleavage Xenopus embryos, we isolated animal and vegetal blastomeres at 8-cell stage, extracted the maternal mRNA respectively and analyzed them by RNA-seq technology. We identified 43 maternal transcripts significa...
ORGANISM(S): Xenopus laevis 
2015-05-19 | E-GEOD-68972 | biostudies-arrayexpress
ProteomicsNeoantigen Discovery and Validation in Hepatocellular Carcinoma: Unveiling Immunogenic Targets Through Mass Spectrometry
The accurate identification of tumor neoantigens, particularly cryptic antigens from non-canonical translation, is crucial for developing effective cancer immunotherapies. However, the significance and action of cryptic antigens in anti-tumour immunity remain unclear. In this study, we utilized a hi...
ORGANISM(S): Rattus Rattus 
2025-07-25 | PXD079354 |
ProteomicsA Recombinant Vaccine Targeting Receptor-binding Domain of SARS-CoV-2 Spike Protein Induces Protective Immunity in Mice and Non-human Primates
The novel Coronavirus SARS-CoV-2 causes a respiratory illness called COVID-19 leading to a pandemic. An effective preventive vaccine against this virus is urgently needed.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
2020-07-30 | PXD020653 |
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