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ProteomicsNeoantigen Discovery and Validation in Hepatocellular Carcinoma: Unveiling Immunogenic Targets Through Mass Spectrometry
The accurate identification of tumor neoantigens, particularly cryptic antigens from non-canonical translation, is crucial for developing effective cancer immunotherapies. However, the significance and action of cryptic antigens in anti-tumour immunity remain unclear. In this study, we utilized a hi...
ORGANISM(S): Rattus Rattus 
2025-07-25 | PXD079354 |
ProteomicsProteomic analysis identifies GSN as non-invasive circulating serum biomarker for predicting early recurrence in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is susceptible to early recurrence and lacks effective predictive markers. Mass Spectrometry (MS)-based proteomics has emerged as a potent tool for identifying cancer biomarker profiles in various bodily fluids. In this study, we established a MS-based biomarker discov...
ORGANISM(S): Homo Sapiens 
2023-12-15 | PXD047852 |
Genomicsena-DATASET-BGI-26-11-2015-07:58:13:440-13 - samples
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
EGAD00001001691 | EGA
GenomicsWhole-genome sequencing in 14 cases and whole-exome sequencing in 90 cases of Chinese ESCC
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
EGAS00001001487 | EGA
ProteomicsMultiomics analysis revealed proteomic subtyping of hepatocellular carcinoma guide the precise therapy of sorafenib
Multiomics analysis revealed proteomic subtyping of hepatocellular carcinoma guide the precise therapy of sorafenib
ORGANISM(S): Homo Sapiens 
2023-10-30 | PXD046519 |
UnknownClimate of origin shapes variations in wood anatomical properties of 17 Picea species.
Not available
S-EPMC11100223 | biostudies-literature
MetabolomicsArginine depletion-induced autophagy and metabolic dysregulation are involved in the disease severity of hand, foot, and mouth disease
Amino acid metabolism provides significant insight into the development and prevention of many viral diseases. Therefore, the present study aimed to compare the amino acid profiles of hand, foot, and mouth disease (HFMD) patients with those of healthy individuals and to further reveal the molecular ...
2024-10-25 | MTBLS11341 | MetaboLights
ProteomicsMass spectrometry identification of interacting proteins of the NP protein from genotype IV NDV Herts/33 and the NP protein from genotype VII NDV strain I4
Newcastle Disease Virus (NDV) is one of the most threatening viruses to the poultry industry, and it also exhibits oncolytic properties. In our research, we identified a non-oncolytic strain, genotype VII NDV strain I4, where the lack of oncolytic ability is attributed to its NP protein. To explore ...
ORGANISM(S): Homo Sapiens 
2023-07-28 | PXD044165 |
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