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ProteomicsModerate-Intensity Interval Exercise Exacerbates Cardiac Lipotoxicity in High-Fat, High-Calories Diet-Fed Mice
Physical exercise is a cornerstone for preventing diet-induced obesity, while it is unclear whether physical exercise could offset high-fat, high-calories diet (HFCD)-induced cardiac dysfunction. Here, mice were fed with HFCD and simultaneously subjected to physical exercise. As expected, physical e...
ORGANISM(S): Mus Musculus 
2024-11-30 | PXD058460 |
ProteomicsMagnesium deficiency accelerates gut aging and increases susceptibility to colitis
Metabolic imbalance drives organ aging and diseases, but the underlying mechanisms remain elusive. Here, we identify magnesium (Mg) deficiency as is a risk factor of gut health with age across species (human, primate, murine). Although Mg restriction had minimal effects in young mice, it exacerbated...
ORGANISM(S): Macaca Fascicularis Fascicularis Mus Musculus 
PXD067494 |
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