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UnknownARMCX1 inhibits lung adenocarcinoma progression by recruiting FBXW7 for c-Myc degradation.
Not available
S-EPMC11406719 | biostudies-literature
ProteomicsMAGL Targeted PROTAC Degrader Simultaneously Enhances P53 for Synergistic Treatment of Glioblastoma Stem Cell
This study focuses on the protein degradation effects of the MAGL inhibitor JZL184 and the newly synthesized MAGL-PROTAC on MAGL.
ORGANISM(S): Homo Sapiens 
2024-12-02 | PXD058506 |
GenomicsGenome-wide maps of Tamoxifen resistance MCF7 cell line
We report the ER alpha regulatory network of Tamoxifen resistance MCF7 cell line using the Chromatin immunoprecipitated high-throughput sequencing technology (ChIP-seq). By Integrating the gene expression data (previously reported) with the ChIP-seq data, we generated ER alpha regulatory network and...
ORGANISM(S): Homo sapiens 
2010-12-20 | E-GEOD-26083 | biostudies-arrayexpress
ProteomicsTargeting RANKL-Independent Osteoclastogenesis Overcomes Denosumab Resistance in ER+ Breast Cancer Bone Metastasis
Bone metastasis remains a major cause of morbidity in ER+ breast cancer, with RANKL inhibitor resistance emerging as a critical clinical challenge. Nearly 40% of patients develop progressive skeletal lesions despite denosumab therapy, highlighting an urgent need to identify resistance mechanisms and...
ORGANISM(S): Homo Sapiens 
2026-01-29 | PXD073739 |
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