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TranscriptomicsResponse of Methicillin-resistant Staphylococcus aureus to Amicoumacin A
Methicillin resistant Staphylococcus aureus (MRSA) infection is becoming refractory to existing antibiotic therapy owing to the inherent ability of S. aureus to develop rapid resistance and is considered a major threat to public health. We found that a natural isolate of Bacillus pumilus from the C...
ORGANISM(S): Staphylococcus aureus 
2012-07-30 | E-GEOD-31342 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human intestinal organoids infected with Salmonella enterica at 2.5h and 8h post infection
The purpose of this experiment was to identify intestinal epithelial responses to various strains of Salmonella enterica. Human intestinal organoids were infected with three serovars of Salmonella; Typhimurium, Enteritidis and Typhi, as well as type 3 secretion system -1 and -2 mutants in Typhimuriu...
ORGANISM(S): Homo sapiens 
2021-10-01 | E-MTAB-10451 | biostudies-arrayexpress
ProteomicsProteogenomic Integration Reveals Therapeutic Targets in Breast Cancer Xenografts
Huang K, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, et al., (2017) Nature Communications | 8:14864 | DOI: 10.1038/ncomms14864 | http://www.nature.com/articles/ncomms14864

Recent advances in mass spectrometry (MS) hav...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084249 | MassIVE
ProteomicsProteomic analysis of extracellular vesicles and conditioned medium from human Adipose-derived Stem/Stromal Cells and Dermal Fibroblasts
Conditioned medium (CM) and extracellular vesicles (EV) from human Adipose-derived Stem/stromal cells (ASC) and Dermal fibroblasts (DF) can represent valid cell substitutes in regenerative medicine and other therapeutic applications. Whether one of the two cell products should be preferred over the ...
ORGANISM(S): Homo sapiens (Human) 
2020-12-23 | PXD020219 | Pride
Adipose-derived stromal cells Label-free quantitative proteomics Extracellular vesicles Dermal fibroblasts Conditioned medium Secretome 
TranscriptomicsGenetic Basis of Transcriptomic Diversity in Drosophila melanogaster
Understanding how DNA sequence variation is translated into variation for complex phenotypes has remained elusive, but is essential for predicting adaptive evolution, selecting agriculturally important animals and crops, and personalized medicine. Here, we quantified genome-wide genetic variation in...
ORGANISM(S): Drosophila melanogaster 
2015-10-05 | E-MTAB-3216 | biostudies-arrayexpress
TranscriptomicsThe Mitochondrial Calcium Uniporter controls skeletal muscle mass in vivo
Muscle atrophy contributes to the poor prognosis of many physiopathological conditions, but pharmacological therapies are still limited. Muscle activity leads to major swings in mitochondrial [Ca2+] which control aerobic metabolism, cell death and survival pathways. We have investigated in vivo the ...
ORGANISM(S): Mus musculus 
2015-03-05 | E-GEOD-60931 | biostudies-arrayexpress
TranscriptomicsEpigenome analysis of patients with various myeloid malignancies including differential levels of 5-hydroxymethylcytosine
TET2 is a close relative of TET1, an enzyme that converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in DNA. The gene encoding TET2 resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral loss of heterozygosity (CN-LOH) in patients with diverse myeloid...
ORGANISM(S): Homo sapiens 
2010-12-11 | E-GEOD-25706 | biostudies-arrayexpress
UnknownLarge single crystal growth, transport property, and spectroscopic characterizations of three-dimensional Dirac semimetal Cd3As2.
Not available
S-EPMC4642520 | biostudies-literature
MetabolomicsObesogenic high-fat diet and MYC cooperate to promote lactate accumulation and tumor microenvironment remodeling in prostate cancer (Murine serum assays)

Cancer cells exhibit metabolic plasticity to meet oncogene-driven dependencies while coping with nutrient availability. A better understanding of how systemic metabolism impacts the accumulation of metabolites that reprogram the tumor microenvironment and drive cancer could facilitate development...

2024-04-10 | MTBLS3316 | MetaboLights
MetabolomicsObesogenic high-fat diet and MYC cooperate to promote lactate accumulation and tumor microenvironment remodeling in prostate cancer (Murine prostate assays)

Cancer cells exhibit metabolic plasticity to meet oncogene-driven dependencies while coping with nutrient availability. A better understanding of how systemic metabolism impacts the accumulation of metabolites that reprogram the tumor microenvironment and drive cancer could facilitate development...

2024-04-10 | MTBLS3317 | MetaboLights
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