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TranscriptomicsGenome plasticity in Streptomyces: identification of 1 Mb TIRs in the S. coelicolor A3(2) chromosome
The chromosomes of several widely used laboratory derivatives of Streptomyces coelicolor A3(2) were found to have 1.06 Mb inverted repeat sequences at their termini (i.e. long-terminal inverted repeats; L-TIRs), which are 50 times the length of the 22 kb TIRs of the sequenced S. coelicolor strain M1...
ORGANISM(S): Streptomyces coelicolor 
2005-07-26 | E-GEOD-2994 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization Streptomyces coelicolor A3(2) strains
The chromosomes of several widely used laboratory derivatives of Streptomyces coelicolor A3(2) were found to have 1.06 Mb inverted repeat sequences at their termini (i.e. long-terminal inverted repeats; L-TIRs), which are 50 times the length of the 22 kb TIRs of the sequenced S. coelicolor strain M1...
ORGANISM(S): Streptomyces coelicolor 
2005-07-21 | E-SMDB-2740 | biostudies-arrayexpress
TranscriptomicsEffect of carbon monoxide and the CO sensor CooA on gene expression in Desulfovibrio vulgaris Hildenborough
Investigating the role of carbon monoxide and a CO sensor protein CooA in the physiology of Desulfovibrio vulgaris Hildenborough using whole genome expression analysis Comparison of whole genome expression changes in the wild type and a strain deleted for CooA (DVU2097) in the presence and absence o...
ORGANISM(S): Desulfovibrio vulgaris str. Hildenborough 
2012-07-30 | E-GEOD-36770 | biostudies-arrayexpress
TranscriptomicsWhole Genome Characterization of Circulating Tumor Cells Identifies Novel Prognostic Genomic Alterations in Melanoma Metastasis
Circulating tumor cells (CTCs) are critical in the development of distant organ tumor metastasis, and are associated with advanced cancer stage and poor patient outcome. Here, we present the first genome-wide nucleotide-level characterization of CTCs. Our single-nucleotide polymorphism (SNP) analysi...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-43934 | biostudies-arrayexpress
TranscriptomicsGenotype profiling of primitive neuroectodermal tumours (250K_Nsp_SNP and 250K_Sty_SNP)
Primitive neuro-ectodermal tumours (PNET) of the supratentorial region are rare, highly malignant embryonal brain tumours affecting young children. Although supratentorial PNET (sPNET) are histologically similar to infratentorial PNET/medulloblastoma, sPNET have more aggressive clinical phenotypes, ...
ORGANISM(S): Homo sapiens 
2009-12-21 | E-GEOD-14087 | biostudies-arrayexpress
TranscriptomicsScl specifies hemogenic endothelium and inhibits cardiogenesis via primed enhancers
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-47085 | biostudies-arrayexpress
UnknownLeveraging platinum-protein interactions to overcome chemoresistance.
Not available
S-EPMC12537935 | biostudies-literature
UnknownAn engineered Sox17 induces somatic to neural stem cell fate transitions independently from pluripotency reprogramming.
Not available
S-EPMC10446497 | biostudies-literature
TranscriptomicsChemokine Transcripts as Targets of the RNA-Binding Protein HuR in Human Airway Epithelium
HuR is a regulator of mRNA turnover or translation of inflammatory genes through binding to adenylate-uridylate-rich elements (ARE) and related motifs present in the 3’untranslated region (UTR) of mRNAs. We aimed to identify HuR targets in the human airway epithelial cell line BEAS-2B challenged wit...
ORGANISM(S): Homo sapiens 
2010-11-10 | E-GEOD-25264 | biostudies-arrayexpress
TranscriptomicsTGF-β Tumor Suppression Through A Lethal EMT
TGF-β is a major tumor suppressor in gastrointestinal (GI) and squamous carcinomas, which exhibit frequent genetic inactivation of Smad4, a key TGF-β signaling component. Apoptosis is implicated as an important mediator of the tumor suppressive function of TGF-β, although this process remains poo...
ORGANISM(S): Mus musculus 
2016-02-24 | E-GEOD-72069 | biostudies-arrayexpress
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