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Wild-type and delta-rpoE strains of H:z66 positive S. Typhi were grown respectively in 1 ml of LB broth (pH 7.0) at 37oC with shaking (200 rpm) overnight. 200 ul of each culture was then transfer-incubated in fresh 20 ml of LB broth to log phase (0.5 OD at 600 nm). Ampicillin was added in cultures t...
ORGANISM(S): Salmonella typhi GIFU10007 
The homeostasis of the inner nuclear membrane (INM) proteins plays a critical role in regulating the nuclear structure, genome integrity, and signal transduction. However, little is known about the turnover of INM proteins in higher eukaryotes. Here we demonstrated that the conserved INM protein SUN...
ORGANISM(S): Arabidopsis Thaliana 
2020-03-11 | PXD015920 |
Phosphoinositide-3-kinase (PI3K)-α inhibitors are clinically active in squamous carcinoma (SCC) of the head and neck (H&N) bearing mutations or amplification of PIK3CA. We aimed to identify potential mechanism of resistance and have observed that SCCs cells overcome the antitumor effects of the PI3K...
ORGANISM(S): Homo sapiens 
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