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ProteomicsIdentification of potential Rsf1 promoter-interacting proteins in rice (Oryza sativa Nipponbare) roots during nematode infection
We performed DNA-pull down experiments using biotin-labeled and unlabeled promoter sequences of Rsf1, a susceptibility factor in rice against root-knot nematode infection, to capture interacting nuclear proteins from rice roots at different time points post-infection (0, 1, and 3 days). Captured pro...
ORGANISM(S): Oryza sativa (Rice) 
2025-12-07 | PXD071646 | Pride
Lc-ms/ms Nuclear proteins. Promoter pull-down Root-knot nematode Dna-protein interaction Rice 
ProteomicsProteomic profiling of rice (Oryza sativa Nipponbare) roots during compatible interaction with the root-knot nematode Meloidogyne graminicola
This study employed label-free quantitative mass spectrometry to investigate the proteomic changes in roots of the susceptible rice cultivar Nipponbare during a compatible interaction with the root-knot nematode Meloidogyne graminicola. Root samples were collected at four time points: before inocula...
ORGANISM(S): Oryza sativa (Rice) 
2025-12-08 | PXD071707 | Pride
Meloidogyne graminicola Plant-pathogen interaction. Label-free quantitative proteomics Compatible interaction Nipponbare Root proteome Rice 
GenomicsThe Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation
The Mediator complex functions as a control center orchestrating diverse signalings, gene activities, and biological processes. However, how Mediator subunits determine distinct cell fates remains to be fully elucidated. Here, we show that Mediator MED23 controls the cell fate preference that direct...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-40369 | biostudies-arrayexpress
TranscriptomicsMediator Complex Regulates Alternative mRNA Processing via the Med23 Subunit
Mediator complex is an integrative hub for transcriptional regulation. Here we show that Mediator regulates alternative mRNA processing via its Med23 subunit. Combining tandem affinity purification and mass spectrometry, we identified a number of mRNA processing factors that bind to a soluble recomb...
ORGANISM(S): Homo sapiens 
2012-02-24 | E-GEOD-33771 | biostudies-arrayexpress
ProteomicsDisrupting metformin adaptation of hepatocellular carcinoma by targeting TOMM34/ATP5B axis
As a well-known anti-diabetic drug, metformin has been repurposed for cancer treatment, but drug resistance and tumor metastasis observed recently have challenged its further application. Here, we found that long-term metformin exposure led to metabolic adaptation of HCC cells, which was characteriz...
ORGANISM(S): Homo Sapiens 
2022-07-14 | PXD035365 |
ProteomicsA Recombinant Vaccine Targeting Receptor-binding Domain of SARS-CoV-2 Spike Protein Induces Protective Immunity in Mice and Non-human Primates
The novel Coronavirus SARS-CoV-2 causes a respiratory illness called COVID-19 leading to a pandemic. An effective preventive vaccine against this virus is urgently needed.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
2020-07-30 | PXD020653 |
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