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TranscriptomicsGenome-wide profiling of gene expression under electro-acupuncture treatment on MI heart in rats
Purpose: Acupuncture exerts cardioprotective effects on several types of cardiac injuries, especially myocardial ischemia (MI). In order to elucidate the potential mechanisms, RNA-seq by next generation sequencing was used to identify the rat genome-wide alterations after MI and EA treatment in t...
ORGANISM(S): Rattus norvegicus 
2016-03-21 | E-GEOD-54132 | biostudies-arrayexpress
ProteomicsBone Morphogenetic Protein 9 Protects against Myocardial Infarction by Improving Lymphatic Drainage Function and Triggering DECR1-Mediated Mitochondrial Bioenergetics
We investigated the impact of both BMP9 deficiency and replenishment on the pathogenesis of MI in mice. Our results showed an aggravated pathological phenotype of MI in BMP9 knockout (KO) mice, which can be alleviated by replenishment of BMP9. Therefore, we further investigated the mechanism whereby...
ORGANISM(S): Mus Musculus 
2024-04-17 | PXD051517 |
UnknownIdentification of circular RNA biomarkers for Pien Tze Huang treatment of CCl4‑induced liver fibrosis using RNA‑sequencing.
Not available
S-EPMC9437966 | biostudies-literature
UnknownLauric acid in crown daisy root exudate potently regulates root-knot nematode chemotaxis and disrupts Mi-flp-18 expression to block infection.
Not available
S-EPMC3883285 | biostudies-literature
TranscriptomicsProgramming and inheritance of parental DNA methylomes in mammals
The reprogramming of parental methylomes is essential for embryonic development. In mammals, paternal 5-methylcytosines (5mCs) have been proposed to be actively converted to oxidized bases. These paternal oxidized bases and maternal 5mCs are believed to be passively diluted by cell divisions. By gen...
ORGANISM(S): Mus musculus 
2014-05-12 | E-GEOD-56697 | biostudies-arrayexpress
UnknownMenin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.
Not available
S-EPMC6994154 | biostudies-literature
TranscriptomicsGene Expression in Transformed Lymphocytes Reveals Phenotype-Modifying Pathways in Cystic Fibrosis
Heritable genetic variants modify cystic fibrosis (CF) clinical phenotypes, e.g., lung disease, age-of-onset of persistent Pseudomonas aeruginosa (P. aeruginosa), and meconium ileus (MI).  Previous genome wide association studies (GWAS) have begun to inform the genetic architecture of CF phenotypes...
ORGANISM(S): Homo sapiens 
2016-05-19 | E-GEOD-60690 | biostudies-arrayexpress
UnknownOxidative Stress-related Gene Signature: A Prognostic Tool for Predicting Survival in ST-elevation MI.
Not available
S-EPMC12060176 | biostudies-literature
TranscriptomicsSperm but not oocyte DNA methylome is inherited by zebrafish early embyros
5-methylcytosine is a major epigenetic modification sometimes called "the fifth nucleotide". However, our knowledge of how offspring inherit the DNA methylome from parents is limited. We generated nine single-base resolution DNA methylomes including zebrafish gametes and early embryos. The...
ORGANISM(S): Danio rerio 
2013-05-20 | E-GEOD-44075 | biostudies-arrayexpress
UnknownGenome-Wide Characterization of PIN Auxin Efflux Carrier Gene Family in Mikania micrantha.
Not available
S-EPMC9456128 | biostudies-literature
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