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TranscriptomicsGenomic-Derived Markers for Early Detection of Calcineurin Inhibitor Immunosuppressant–Mediated Nephrotoxicity
The use of calcineurin inhibitor (CI) immunosuppressants has significantly improved the early allograft survival rate in organ transplantation. However, CI therapy has been associated with chronic nephrotoxicity, which limits their long-term utility. In order to understand the mechanisms of the toxi...
ORGANISM(S): Rattus norvegicus 
2011-11-23 | E-GEOD-19366 | biostudies-arrayexpress
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownRisk for recurrent cardiovascular disease events among patients with diabetes and chronic kidney disease.
Not available
S-EPMC7923492 | biostudies-literature
UnknownThe Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology.
Not available
S-EPMC7887805 | biostudies-literature
UnknownAnalytical Quality Evaluation of the Tox21 Compound Library.
Not available
S-EPMC11752516 | biostudies-literature
UnknownEditor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.
Not available
S-EPMC6280881 | biostudies-literature
ProteomicsA framework for quality control in quantitative proteomics
A thorough evaluation of the quality, reproducibility, and variability of bottom-up proteomics data is necessary at every stage of a workflow, from planning to analysis. We share vignettes applying adaptable quality control (QC) measures to assess sample preparation, system function, and quantitativ...
ORGANISM(S): Homo Sapiens Mus Musculus Bos Taurus Saccharomyces Cerevisiae 
PXD051318 | panorama
UnknownDesign and Baseline Characteristics of the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease Trial.
Not available
S-EPMC6888890 | biostudies-literature
UnknownFinerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes According to Baseline HbA1c and Insulin Use: An Analysis From the FIDELIO-DKD Study.
Not available
S-EPMC9271031 | biostudies-literature
UnknownFinerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes by Sodium-Glucose Cotransporter 2 Inhibitor Treatment: The FIDELITY Analysis.
Not available
S-EPMC9862372 | biostudies-literature
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