Huang Tim H M TH

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Genome-wide mapping of RNA Pol-II promoter usage in mouse tissues by ChIP-seq

We report active promoters in five adult mouse tissues - brain, kidney, liver, lung and spleen using ChIP-Seq aganist RNAP-II antibody. We identified 38,639 active RNAP-II transcribed promoters, including 12,270 novel promoters. Of these, 6384 promoters are tissue specific which are CpG poor and con...

ORGANISM(S): Mus musculus

2010-09-07 | E-GEOD-21773 | biostudies-arrayexpress

Coordinate Enhancer Reprogramming by GATA3 and AP1 Promotes Phenotypic Plasticity to Achieve Breast Cancer Endocrine Resistance

Phenotypic plasticity has emerged as an important mechanism of therapy resistance in cancers, yet the underlying molecular mechanisms remain unclear. Using an established breast cancer cellular model for endocrine resistance, we show that hormone resistance is associated with enhanced phenotypic pla...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2019-05-24 | MSV000083857 | MassIVE

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis.

Not available

S-EPMC9333998 | biostudies-literature

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Not available

S-EPMC7350392 | biostudies-literature

Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.

Not available

S-EPMC11872607 | biostudies-literature

Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.