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TranscriptomicsBJAB Cell Lines Unmodified, Transduced with ith lentiviral vector pNL-SIN-CMV-AcGFP or pNL-SIN-CMV-AcGFP/miR-K12-11
All metazoan eukaryotes express microRNAs (miRNAs), ~22 nt long regulatory RNAs that can repress the expression of mRNAs bearing complementary sequences. Several DNA viruses also express miRNAs in infected cells, suggesting a role in viral replication and pathogenesis. While specific viral miRNAs ha...
ORGANISM(S): Homo sapiens 
2007-12-18 | E-GEOD-8867 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of Drosophila neural stem cells reveals a transcriptional network for self-renewal.
Drosophila neuroblasts have emerged as a model for stem cell biology that is ideal for genetic analysis but is limited by the lack of cell-type specific gene expression data. Here, we describe a methodology to isolate large numbers of pure neuroblasts and differentiating neurons that retain both cel...
ORGANISM(S): Drosophila melanogaster 
2012-08-21 | E-GEOD-38764 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human synovial samples from patients with osteoarthritis, rheumatoid arthritis vs controls treated with various drug regimes to characterise RA at the molecular level and to uncover key pathomechanisms
Rheumatoid arthritis (RA) is a chronic, inflammatory joint disease of unknown etiology and pronounced inter-patient heterogeneity. To characterize RA at the molecular level and to uncover key pathomechanisms, we performed whole-genome gene expression analyses. Synovial tissues from rheumatoid arthri...
ORGANISM(S): Homo sapiens 
2004-11-04 | E-GEOD-1919 | biostudies-arrayexpress
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