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TranscriptomicsThe transcriptomic response of E. coli to triclosan exposure
The gene expression profile of E. coli K-12 MG1655 grown in minimal medium treated with 0.12 mg/L of the biocide triclosan has been analysed using whole genome oligonucleotide microarrays. "Control" RNA was isolated from three independently grown 50ml MOPS minimal media cultures of E. coli K-12 MG16...
ORGANISM(S): Escherichia coli 
2010-10-08 | E-GEOD-15059 | biostudies-arrayexpress
ProteomicsProteome of senescent human lung fibroblasts and Panc-1 cells
Proteomic analysis of proliferating and senescent normal healthy lung fibroblasts (NHLFs) and Panc-1 cells. Senescence was induced using 5 uM Palbociclib for 6 days. Cells were lysed in SDS lysis buffer (2% SDS in 100 mM TEAB), boiled (15 min, 95 °C, 500 rpm) and sonicated in a sonication bath (10 ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-10-28 | MSV000090607 | MassIVE
TranscriptomicsOverexpression of c-Jun in mouse Schwann cells of uninjured nerves
Two mouse lines, OE/+ and OE/OE were generated expressing graded elevation (6 fold and 28 fold, respectively) of c-Jun protein selectively in Schwann cells. The effects of this on global gene expression and cellular structure in uninjured nerves was analysed during development and in the adult. Chan...
ORGANISM(S): Mus musculus 
2017-10-16 | E-MTAB-6138 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat intact CNS tissue in vitro using rat organotypic hippocampal slice cultures after anti-Nogo-A antibody treatment
The neurite outgrowth inhibitory myelin protein Nogo-A has been well studied in the context of central nervous system (CNS) injury and disease. We studied the effects of the application of neutralizing anti-Nogo-A antibodies (11C7 and 7B12) in intact CNS tissue in vitro using rat organotypic hippoca...
ORGANISM(S): Rattus norvegicus 
2008-11-15 | E-GEOD-12483 | biostudies-arrayexpress
ProteomicsCharacterization of Equine Platelet Lysate for Nebulization in the Horse
Platelet lysate (PL) demonstrates antimicrobial and anti-inflammatory properties and may offer potential for treatment of bacterial pneumonia in horses. It remains unknown whether nebulization represents a suitable method of administration of PL in horses. This study characterized particle size and ...
ORGANISM(S): Equus Caballus 
2024-12-26 | PXD055023 | JPOST Repository
ProteomicsThe Nα-acetyltransferase NAA50 mediates plant immunity independent of the NatA complex
Nα-terminal acetylation (NTA) ranges among the most abundant protein modifications in higher eukaryotes. Over 40 % of the human and plant proteome are co-translationally acetylated by a single Nα-acetyltransferase (Nat) termed NatA. The core NatA complex consists of the catalytic subunit NAA10 and t...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2024-03-01 | PXD040755 | JPOST Repository
TranscriptomicsActivation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective. doi: 10.1038/nm.4109
The multiple claims about reactivation of the embryonic stem cell (ESC) pluripotency factor OCT4 in somatic cells are highly controversial due to the fact that there is no direct evidence that OCT4 has a functional role in cells other than ESCs. Herein we demonstrate that smooth muscle cell (SMC)-sp...
ORGANISM(S): Mus musculus 
2016-05-15 | E-GEOD-75044 | biostudies-arrayexpress
TranscriptomicsFunctional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
Expression profiles of human cortical spheroids (hCSs) derived from pluripotent stem cells using Illumina cDNA microarrays. The goal of the study is to assess the developmental maturity and the regional identity of those hCSs at two distinct time points with expression profiles and compare the expre...
ORGANISM(S): Homo sapiens 
2015-05-25 | E-GEOD-68917 | biostudies-arrayexpress
UnknownGuidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Not available
S-EPMC7350392 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
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