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TranscriptomicsExpression Data from BALB/c and Stat6-deficient bone marrow derived macrophages (BMDM)
We used microarrays to find Stat6 dependent genes in control and IL-4 exposed bone marrow derived macrophages. Alternatively activated macrophages (AAM) accumulate in tissues during Th2-associated immune responses like helminth infections and allergic disorders. These cells possess potent inhibitor...
ORGANISM(S): Mus musculus 
2010-07-19 | E-GEOD-20030 | biostudies-arrayexpress
MetabolomicsMetabolome analysis via an HPLC-ESI-MS-based experimental and computational pipeline for chronic nephron toxicity profiling
Untargeted metabolomics has the potential to improve the predictivity of in vitro toxicity models and therefore may aid the reduction of expensive and laborious animal models. Here we describe a chronic nephrotoxicity study conducted on a human renal proximal tubular epithelial cell line (RPTEC/TERT...
2015-09-07 | MTBLS140 | MetaboLights
TranscriptomicsChromatin immunoprecipitation to identify binding sites for Gata4, Mef2a, Nkx2.5, Srf, p300, Pol_II, H3ac, H3K4me1 in mouse cardiomyocyte cell line, HL1
The aim of the experiment was to identify genome wide binding sites for Gata4, Mef2a, Nkx2.5, Srf, p300, Pol_II, H3ac, H3K4me1 by using Chromatin Immunoprecipitation followed by microarray analysis (ChIP-chip) in HL1 cells.
ORGANISM(S): Mus musculus 
2011-01-05 | E-TABM-378 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of mouse HL1, C2C12 differentiated and C2C12 undifferentiated cells with four histone modifications
The combinatorial effects of four histone modifications in transcription and differentiation. Two replicates per histone modification and cell type.
ORGANISM(S): Mus musculus 
2007-10-17 | E-TABM-182 | biostudies-arrayexpress
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